METHOD AND APPARATUS FOR ION MOBILITY SEPARATIONS UTILIZING ALTERNATING CURRENT WAVEFORMS

Patent ID: 9731 | Patent Number 11,209,393 | Status: Granted

Abstract

We developed a new device that can be utilized to perform efficient and versatile control of ion motion in the gas phase. The new device can be used to perform high resolution gas-phase ion mobility separation. The device can be also utilized to perform variety of ion manipulations such as trapping, switching, dissociation, reactions, etc. The ion manipulations are performed between two surfaces where appropriate RF and DC fields are applied to control the ion motion. The new device utilizes arrays of electrodes on two or more surfaces where a transient DC waveform is applied to array of DC electrodes to propel and control ions through the device. In one embodiment the confinement of ions inside the device is achieved by applying a radio frequency (RF) waveform to array of electrodes that are inserted between the arrays of DC electrodes. The new device allows flexibility of laying different electrode arrangements to perform different ion manipulations. A proof-of-concept experiment demonstrated an extremely high mobility resolution in a platform of a small footprint. The new device also allows the construction of extended 3 dimensional structures as well as miniaturization with ease.

Application Number

16/404,472

Inventors

Hamid,Ahmed M
Smith,Richard D
Ibrahim,Yehia M
Garimella,Sandilya

Market Sector

Analytical Instruments