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  1. Research
  2. National Security

National Security

Identifying and combating
complex threats

Image by Timothy Holland | Pacific Northwest National Laboratory

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Protecting U.S. residents is among our nation’s highest priorities. As adversaries gain access to sophisticated technologies and materials, the threats grow more dynamic and complex—from cyber and nuclear to chemical and biological weapons of mass destruction and other forms of terrorism.

Faced with these realities and their impact on national security, PNNL develops science-based solutions that keep America safe. We drive innovation and critical capabilities in nuclear materials, threat analysis, and other areas of expertise to secure our nation’s critical infrastructure, combat global terrorism, and detect concealed threats and explosives.

The PNNL national security mission connects back to the 1940s, when scientists in nearby Hanford, Washington, produced the nation’s first plutonium for the Manhattan Project. Today, our researchers, tools, and technologies play a key role in advancing the ability to identify and secure nuclear materials, detect weapons of mass effect, manage nonproliferation treaties, secure our nation's borders, and protect critical infrastructures. 

PNNL’s scientific discovery and capabilities—rooted in innovative theory, methods, algorithms, and tools—are enabling stronger, more resilient technologies and systems to safeguard national security. Coupled with decades of radiological and nuclear materials expertise, advanced computing and threat analysis capabilities, we are delivering solutions to identify, understand, and mitigate emerging threats at home and around the globe.

By the Numbers: National Security Related Research, Fiscal Year 2024

Scientists, engineers, and professional staff icon

1,758

Scientists, engineers, and professional staff

R&D funding logo

$759M

science and technology funding

U.S. and foreign patents granted logo

21

U.S. and foreign patents granted

R&D 100 Awards logo

2

R&D 100 Awards

WSU-PNNL Nuclear Science and Technology Institute logo

1

Federal Laboratory Consortium Award

Peer-reviewed publications logo

209

Peer-reviewed publications

Invention disclosures logo

112

Invention disclosures

Countries where PNNL staff engaged virtually logo

100+

Countries where PNNL staff engaged virtually

Copyrights and trademarks granted logo

22

Copyrights and trademarks granted

Joint appointments between PNNL and other research institutions logo

29

Joint appointments between PNNL and other research institutions

Postdocs logo

32

Postdocs

530

Interns / limited term employees

Latest News

JUNE 19, 2025
Staff Accomplishment

Laura di Vacri Joins the Coordinating Panel for Advanced Detectors

Read
Laura di Vacri
JUNE 5, 2025
Staff Accomplishment

New Co-director Selected for PNNL-Georgia Tech Joint Research Institute

Read
Danny Herrera
JUNE 4, 2025
Feature

Launching a Generation of National Security Leaders

Read
NGFP 30th Logo
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Facilities

Radiochemical Processing Laboratory Shallow Underground Laboratory Systems Engineering Building Advanced Wireless Communications Lab

Related Divisions

AI and Data Analytics Division
Emerging Threats and Technologies Division
Nuclear, Chemical, and Biological Technologies Division
Physical Detection Systems and Deployment Division

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