The Ion Dynamics in Radioactive Environments and Materials (IDREAM) Energy Frontier Research Center (EFRC) conducts fundamental science to support innovations in retrieving and processing high-level radioactive waste.

PNNL is heavily engaged in the development and use of mass spectrometry technology across its science, energy, and security missions, from fundamental research through mature operational capabilities.

The Molecular Observation Network is a national open science network designed to produce a comprehensive database of molecular and microstructural information on soil, water, microbial communities, and biogenic emissions.

Pacific Northwest National Laboratory has pioneered the use of observational research for evaluating energy efficient technologies in the built environment.