PNNL is heavily engaged in the development and use of mass spectrometry technology across its science, energy, and security missions, from fundamental research through mature operational capabilities.

The Pacific Northwest Center for Cryo-EM electron microscopy is a user facility operated jointly by PNNL and Oregon Health & Science University.

Using a reverse genome strategy to target the molecular basis of function.

The RD2C laboratory-directed research initiative seeks to develop resilient, adaptive, and intelligent sensing and control algorithms through the observational understanding and characterization of CPSs under adverse conditions.