Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

From producing radioisotope generators to recovering source materials, researchers are meeting a growing need for medical radioisotopes.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Alex Beliaev, a biologist at PNNL, was named a Society for Industrial Microbiology and Biotechnology fellow.

Dušan Veličković, a PNNL mass spectrometry imaging scientist received a $2.1 million grant to develop techniques to understand how changes in carbohydrate structure affect human health.

Researchers from PNNL and Parallel Works, Inc., applied machine learning methods to predict how much oxygen and nutrients are used by microorganisms in river sediments.

This study used historical data, remote sensing, and aquatic sensors to measure how far wildfire impacts propagated through the watershed after the 2022 Hermit’s Peak/Calf Canyon fire, New Mexico’s largest wildfire in history.

The Coastal Observations, Mechanisms, and Predictions Across Systems and Scales: Field, Measurements, and Experiments project established a network of observational field sites across Chesapeake Bay and western Lake Erie.

PNNL has created and licensed a system that sniffs out trace levels of fentanyl, other drugs and explosives through the air.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Directionally biased electrostatic interactions are the key to significantly tuning the reduction potential of iron/sulfur clusters.

A new study led by PNNL researcher TC Chakraborty provides some answers about how irrigated agricultural land near cities affects urban heat stress.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

PNNL is hosting a scientific conference focused directly on understanding and predicting the collection of an organism’s traits.

Circadian rhythms of blue-green microbes offer new window into predictive phenomics—how to predict and control the traits of an organism.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Over the next four years, PNNL and University of Arizona will develop open-source computational tools to better identify and characterize the viruses associated with the human microbiome.