Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

PNNL is hosting a scientific conference focused directly on understanding and predicting the collection of an organism’s traits.

Circadian rhythms of blue-green microbes offer new window into predictive phenomics—how to predict and control the traits of an organism.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

PNNL and collaborators developed new models—recently approved by the U.S. Western Electricity Coordinating Council (WECC)—to help utilities understand how new grid-forming inverter technology will enhance grid stability.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

If you’re not sure whether rooftop solar panels and battery energy storage systems are right for you, start with this new guide from PNNL researchers.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Understanding the risk of compound energy droughts—times when the sun doesn’t shine and the wind doesn’t blow—will help grid planners understand where energy storage is needed most.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.