Pacific Northwest National Laboratory scientists envision new research frontiers at the intersection of biology and AI

Structural proteomics reveal how cyanobacteria adapt to changing light.

Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

PNNL researchers are opening up a new front in the fight to stop viral pathogens, protecting people against multiple viruses.

Capturing protein structural changes in host cells exposes vulnerabilities exploited by viruses to hijack cellular machinery.

Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

From producing radioisotope generators to recovering source materials, researchers are meeting a growing need for medical radioisotopes.

PNNL scientist James Stegen and an international team of collaborators recently published a comprehensive review of variably inundated ecosystems (VIEs).

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

A new study led by PNNL researcher TC Chakraborty provides some answers about how irrigated agricultural land near cities affects urban heat stress.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

CACTUS provides AI-powered cheminformatics for autonomous science.

This project sought to assure that research activities centered around different sampling and monitoring efforts in northwest Ohio would not disturb any historical cultural resources.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Scientists are using artificial intelligence and powerful computing to sculpt new molecules in an effort to treat disease.

PNNL chief data scientist Lauren Charles participated in a science-focused panel linked to the 79th session of the United Nations General Assembly.

Controlling the nanostructure of silk fibroin—a protein found in silk—is a key step toward designing and fabricating electronics that leverage the material’s promising mechanical, optical and biocompatible properties.