Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

PNNL is hosting a scientific conference focused directly on understanding and predicting the collection of an organism’s traits.

Circadian rhythms of blue-green microbes offer new window into predictive phenomics—how to predict and control the traits of an organism.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

At the Nonproliferation, Counterproliferation, and Disarmament Science Gordon Research Conference, researchers from PNNL shared research and scientific approaches for countering diverse threats.

PNNL researchers develop software that uses geographical data to build a free, open-source grid reference system to provide a precise system to locate structures.

PNNL’s Intelligent Load Control technology manages and adjusts electricity use in buildings when there’s peak demand on the power grid.

Following the energy crisis of 2000-2001, the State of Washington received financial settlements from six energy companies, a fraction of which was used for energy-efficiency research.