Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

At the Nonproliferation, Counterproliferation, and Disarmament Science Gordon Research Conference, researchers from PNNL shared research and scientific approaches for countering diverse threats.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Research organizations work toward compelling market-ready solutions for building operations.

The nested nanoPOTS chip is the next generation of technology developed at PNNL to prepare single cells for proteomics.

PNNL-developed Water Balance Tool estimates consumption for major water end-uses. Understanding the breakout of water use identifies water efficiency opportunities and allows facility managers to spot potential system losses.

Buildings account for around 40 percent of our nation's energy use and consume 75 percent of our nation’s electricity each year. Energy use is also one of the biggest costs for facility owners.

PNNL’s longstanding grid and buildings capabilities are driving two projects that test transactive energy concepts on a grand scale and lay the groundwork for a more efficient U.S. energy system.

PNNL’s Intelligent Load Control technology manages and adjusts electricity use in buildings when there’s peak demand on the power grid.

Following the energy crisis of 2000-2001, the State of Washington received financial settlements from six energy companies, a fraction of which was used for energy-efficiency research.