Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

PNNL's accomplishments in FY 2024 help address the remaining challenges the wind industry faces.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

PNNL had a significant presence at October’s North American Wind Energy Academy/WindTech 2023 Conference in Denver, Colorado. Thirteen PNNL wind experts participated in various capacities.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

A research buoy managed by PNNL has been deployed in Hawai’ian waters, collecting oceanographic and meteorological measurements off the coast of O’ahu.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

Multidisciplinary teams from research and industry are brought together using management systems developed by a team of software engineers at PNNL.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

The nested nanoPOTS chip is the next generation of technology developed at PNNL to prepare single cells for proteomics.

Customized molecular tools identify specific microbial functions that are key to healthy people and environments.

PNNL’s Data Archive and Portal that stores and disseminates wind energy data recently reached a major milestone: 1,000 users and growing.

PNNL deployed two research buoys in waters off the West Coast for the first time in deep water, supporting a DOE and Bureau of Ocean Energy Management effort to gather measurements that support offshore wind locations and technologies.

PNNL scientists are learning how to harness wind to secure a brighter, cleaner energy future.