Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

PNNL's Alison Colotelo receives award from the National Hydropower Association on behalf of Salmon Summit team at the 2024 Clean Currents conference.

A new mini-acoustic transmitter and tagging procedure is able to provide data on small, sensitive fish species like the American shad.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

New methodological approach demonstrates how to assess the economic value, including non-traditional value streams, of converting non-powered dams to hydroelectric facilities.

New research identifies the most important factors in successful fish passage, pointing toward new options for flexible dam operations.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

Developed with community input, the new Hydropower Vision Roadmap lays out a path to achieve a shared vison for modern hydropower by 2050.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

Daniel Deng, mechanical engineer and Laboratory Fellow at PNNL, has been named 2022 PNNL Inventor of the Year.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

Fish biologist Brenda Pracheil has been named chair of the Low Impact Hydropower Institute focused on reduction of impacts of hydropower dams on the environment.

Near-real-time fish tracking using a new acoustic receiver developed by PNNL can support enhanced fish passage through hydropower dams.

A new fitness tracker that’s very much like a ‘Fitbit for fish’ is revealing new information about fish health and behavior.

Study highlights microbiome’s role in regulating xenobiotic metabolism.