Shear Assisted Processing and Extrusion (ShAPE) imparts significantly more deformation compared to conventional extrusion. The latest ShAPE system at PNNL, ShAPEshifter, is a purpose-built machine designed for maximum configurability.

Directionally biased electrostatic interactions are the key to significantly tuning the reduction potential of iron/sulfur clusters.

Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

Researchers used a combination of sophisticated laboratory incubations and field measurements to determine the role of microbial production and consumption of methane in soils with different exposure to tidal inundation

Researchers devised a quantitative and predictive understanding of the cloud chemistry of biomass-burning organic gases helping increase the understanding of wildfires.

Reproducible workflows for binning and visualizing nuclear magnetic resonance spectra from environmental samples.

Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.

A streamlined informatics workflow that automatically processes complex data and provides the locations of double bonds in lipids.

Hi-C metagenomics-informed phage-host infection networks detected in soil pre- and post-drying.

Soil is a massive reservoir of carbon, holding three times the amount of carbon than in the atmosphere. Soil is a massive reservoir of carbon, holding three times the amount of carbon than in the atmosphere.

Metabolism metrics provide information about biological activity and carbon cycling in rivers. Conditions in large rivers differ from smaller rivers and require adjustments to existing methods.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

High fidelity simulations enabled by high-performance computing will allow for unprecedented predictive power of molecular level processes that are not amenable to experimental measurement.

The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Across the United States, organic carbon concentration imposes a primary control on river sediment respiration, with additional influences from organic matter chemistry.

Small teams in the Biological Sciences Division at PNNL and at EMSL—the Environmental and Molecular Sciences Laboratory, an Office of Science user facility at PNNL—are pros at preparation.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

The ChemSpace Tool, when fully developed, is intended to divide chemical space into three subsets: the detectable space, the identifiable space, and the region that includes compounds that are not detectable or identifiable.