Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

In the latest issue of the Domestic Preparedness Journal, Ashley Bradley and Kristin Omberg share how new research is shedding light on the scientific and technological challenges with detecting fentanyl.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

PNNL is supporting the Department of Homeland Security Science and Technology Directorate's Chemical Security Analysis Center in improving capabilities to enhance detection and analysis of chemical threats.

A new report highlights the results of an assessment PNNL conducted of field-portable detection products used by first responders to detect illicit substances like fentanyl in the field.

A team of researchers from PNNL provided technical knowledge and support to test a suite of techniques that detect genetically modified bacteria, viruses, and cells.

PNNL researchers are key contributors to GAO report

The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.

The ChemSpace Tool, when fully developed, is intended to divide chemical space into three subsets: the detectable space, the identifiable space, and the region that includes compounds that are not detectable or identifiable.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

ICON science is a Department of Energy-developed framework to enhance scientific outcomes via more intentional design of research efforts across all domains of science.

A new microbial community model reveals previous exposure to hydrologic variation influences a species’ specialized biogeochemical functions.

Detailed characterization of molecules in, under, and along the Columbia River reveal potential mechanisms for biogeochemical cycling.

Integrating hydrogeology and biogeochemistry are required to model the dynamics of geochemical processes occurring in river corridor zones where groundwater and surface water mix.

Theoretical analysis reveals flow variations that happen over longer time periods affect a plume’s spread and center of mass.

Principles derived from coastal wetlands to describe wetland channel cross-sections were applicable to the Columbia River estuary, but not the tidal river.

An updated version of a widely used database will provide powerful insights into the global carbon cycle.

Variability in field measurement conditions likely does not impact estimates of an important flux in the global carbon cycle.

Pacific Northwest marsh carbon stocks are twice the global average. Long-term sea-level rise impacts will likely decrease ecosystem carbon stocks.