By selectively stabilizing either a right- or left-handed helical pose of its substrate, an enzyme tunes the final product.

Five PNNL innovations earned 2026 R&D 100 Awards for advances in biotechnology, manufacturing, critical minerals, and nuclear security.

Novel Applications for Synchronized Power Instrumentation seeks to improve electric grid resilience, reliability, security, and affordability.

Secretary Wright visited PNNL's campus in Richland, Washington, late last year to meet with innovators in chemistry, biology, computing, and more.

PNNL researchers Daniel Deng and Yehia Ibrahim join the 2025 class of National Academy of Inventors Fellows.

CESER and PNNL convened a three-day summit with more than 100 state officials, cybersecurity experts, and industry leaders across 35 states to advance energy security planning, cyber risk assessment, and fortify protections against attacks.

Directionally biased electrostatic interactions are the key to significantly tuning the reduction potential of iron/sulfur clusters.

Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

PNNL computing experts Robert Rallo and Court Corley contribute their knowledge to a recent DOE report on applications of AI to energy, materials, and the power grid.

Researchers used a combination of sophisticated laboratory incubations and field measurements to determine the role of microbial production and consumption of methane in soils with different exposure to tidal inundation

Researchers devised a quantitative and predictive understanding of the cloud chemistry of biomass-burning organic gases helping increase the understanding of wildfires.

Reproducible workflows for binning and visualizing nuclear magnetic resonance spectra from environmental samples.

Pacific Northwest National Laboratory launches the Training Outreach and Recruitment for Cybersecurity Hydropower program at the University of Texas at El Paso.

Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.

A streamlined informatics workflow that automatically processes complex data and provides the locations of double bonds in lipids.

Hi-C metagenomics-informed phage-host infection networks detected in soil pre- and post-drying.

Soil is a massive reservoir of carbon, holding three times the amount of carbon than in the atmosphere. Soil is a massive reservoir of carbon, holding three times the amount of carbon than in the atmosphere.

Metabolism metrics provide information about biological activity and carbon cycling in rivers. Conditions in large rivers differ from smaller rivers and require adjustments to existing methods.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.