Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.
Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.
Discovering and measuring the spatial organization of proteins within cells allows scientists to map complex proteoforms across tissues with near-cellular resolution.
PNNL helps deliver efficiency-related rules and requirements that steadily improve performance of America’s buildings, saving energy and costs and reducing carbon emissions.
Mandy Mahoney, director of the DOE Building Technologies Office, visited PNNL in late November. One key agenda item involved meeting with staff for a discussion of effective equity and justice integration in buildings-related research.
Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.
The PNNL-managed Building America Solution Center translates research into actionable considerations for homeowners and builders to provide two solutions in one: increasing energy efficiency while also enhancing disaster resistance.
This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.
A PNNL team’s analysis of new-housing data concludes that single-family homes in lower-income counties are less energy-code-compliant than in higher-income counties, a finding that could shape strategies for enhanced code adoption.
New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.
COVID-19 infections at PNNL early in the pandemic were caused by a wide variety of viral sequences, according to a new analysis by Laboratory researchers.
Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.
Staff at PNNL recently completed a report highlighting commercial products enabled through projects funded by the Department of Energy’s Building Technologies Office.
