Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.
High fidelity simulations enabled by high-performance computing will allow for unprecedented predictive power of molecular level processes that are not amenable to experimental measurement.
The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.
Scientists can now generate a protein database directly from proteomics data gathered from a specific soil sample using a digital tool and deep learning computer model called Kaiko.
This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.
Across the United States, organic carbon concentration imposes a primary control on river sediment respiration, with additional influences from organic matter chemistry.
Small teams in the Biological Sciences Division at PNNL and at EMSL—the Environmental and Molecular Sciences Laboratory, an Office of Science user facility at PNNL—are pros at preparation.
New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.
The popular approach of organizing soil bacteria into fast- or slow-growing groups is problematic because most bacteria grow at comparable rates in soil.
The ChemSpace Tool, when fully developed, is intended to divide chemical space into three subsets: the detectable space, the identifiable space, and the region that includes compounds that are not detectable or identifiable.
SAGE is a high-efficiency genome integration strategy for bacteria that makes the stable introduction of new traits simple for newly discovered microbes.
Variations in burn severity are a key control on the chemical constituents of dissolved organic matter delivered to streams within a single burn perimeter.
A PNNL innovation uses steam to recover heat from the high-temperature reactor effluent in the HTL process, substantially reducing the propensity for fouling and potentially reducing costs.
Department of Energy, Office of Science Director Asmeret Asefaw Berhe visited PNNL to learn about the Lab’s drive to conduct discovery science, commitment to science for an equitable future, and development of a diversified STEM workforce.
A multi-omics analysis provides the framework for gaining insights into the structure and function of microbial communities across multiple habitats on a planetary scale
A rich and largely untapped reservoir of lipids in soil environments was used to examine microorganisms’ physiological responses to drying-rewetting cycles.
