NUCLEAR REACTOR ASSEMBLIES, NUCLEAR REACTOR TARGET ASSEMBLIES, AND NUCLEAR REACTOR METHODS (iEdison No. 0685901-16-0012)
Reactor target assemblies are provided that can include a housing defining a perimeter of at least one volume and Np or Am spheres within the one volume. Reactor assemblies are provided that can include a reactor vessel and a bundle of target assemblies within the reactor vessel, at least one of the target assemblies comprising a housing defining a volume with Np or Am spheres being within the volume. Irradiation methods are also provided that can include irradiating Np or Am spheres within a nuclear reactor, then removing the irradiated spheres from the reactor and treating the irradiated spheres.
SYSTEM AND PROCESS FOR PURIFICATION OF ASTATINE-211 FROM TARGET MATERIALS (iEdison No. 0685901-17-0014)
A new column-based purification system and approach are described for rapid separation and purification of the alpha-emitting therapeutic radioisotope .sup.211At from dissolved cyclotron targets that provide highly reproducible product results with excellent .sup.211At species distributions and high antibody labeling yields compared with prior art manual extraction results of the prior art that can be expected to enable enhanced production of purified .sup.211At isotope products suitable for therapeutic medical applications such as treatment of cancer in human patients.
DEVICES AND PROCESS FOR HIGH-PRESSURE MAGIC ANGLE SPINNING NUCLEAR MAGNETIC RESONANCE
A high pressure magic angle spinning (MAS) NMR capability, compromising of a high pressure MAS rotor, a high pressure loading/reaction device for in situ sealing and re-opening of the valve of the high pressure MAS rotor, and a MAS probe with localized RF coil for background signal suppression, is reported. Use ceramics as the sample rotor cylinder, and plastics glued in a “smart way” at the both ends of the cylinder for high pressure seal, pressure exceeding 100 bars is achieved with minimal penetration loss of pressure during a period of 72 hours. As an example of application, in situ 13C MAS NMR studies of the reaction products and intermediates associated with geological carbon sequestration using a model mineral, i.e., forsterite (Mg2SiO4) reacted with supper critical CO2 and H2O at 50C are carried out and preliminary results are reported.
SYSTEM AND PROCESS FOR DISSOLUTION OF SOLIDS
A system and process are disclosed for dissolution of solids and “difficult-to-dissolve” solids. A solid sample may be ablated in an ablation device to generate nanoscale particles. Nanoparticles may then swept into a coupled plasma device operating at atmospheric pressure where the solid nanoparticles are atomized. The plasma exhaust may be delivered directly into an aqueous fluid to form a solution containing the atomized and dissolved solids. The composition of the resulting solution reflects the composition of the original solid sample.
PREDICTION OF SOCIAL MEDIA POSTINGS AS TRUSTED NEWS OR AS TYPES OF SUSPICIOUS NEWS
We build predictive models to classify thousands of news posts as suspicious or verified, and predict four subtypes of suspicious news on twitter - satire, hoaxes, clickbait and propaganda. We show that neural network models trained on tweet content and social network interactions outperform lexical models. Unlike previous work on deception detection, we find that adding syntax and grammar features to our models does not improve performance. Incorporating linguistic features improves classification results, however, social interaction features are most informative for finer-grained separation between four types of suspicious news posts.
SYSTEMS AND METHODS FOR DATA STORAGE AND RETRIEVAL
A method includes directing a probe beam to a target that includes an array of data portions in a data storage medium arranged so that a beam area of the probe beam extends across a plurality of adjacent data portions, the array including a data portion subset with each data portion of the subset responsive to the probe beam to produce a response illumination, receiving the response illumination at a detector, and determining data values corresponding to the plurality of adjacent data portions based on the received response illumination. Apparatus and systems are also disclosed.density.
Combinatorial Evaluation of Systems Including Decomposition of a System Representation Into Fundamental Cycles
We construct an algebraic-combination model of networks-of-networks. A Petri net is used to construct an initial representation of the decision-making network, which in turn defines a hyperdigraph. We observe that the linear algebraic structure of each hyperdigraph admits a canonical set of algebraic-combinatorial invariants that correspond to the information flow conservation laws governing a kinetic network. The linear algebraic structure of the hyperdigraph and its sets of invariants can be generalized to define a discrete algebraic-geometric structure, which is referred to as an oriented Matroid. Oriented matroids define a polyhedral optimization geometry that is used to determine optimal subpaths that span the nullspace of a set of kinetic equations. Sets of constrained submodular path optimizations on the hyperdigraph are objectively obtained as a spanning tree of minimum cycle paths. This complete set of subcircuits is used to identify the network pinch points and invariant flow subpaths. We demonstrate that this family of minimal circuits also characteristically identifies additional significant pattern features. We used several applications (including the biochemistry of the Krebs Cycle, the SOS Compartment A of the EGFR biochemical pathway, and economics-driven electric power grids) to develop and demonstrate the application of our algebraic-combinatorial mathematical modeling methodology.
FLEXIBLE ION CONDUIT
The invention is a device for the movement of ions from one location to another with high efficacy. The conduit consists of a tube or other shaped extended structure through with ions move in a gas from one location to another. The tube or the shaped conduit has an inner surface patterned with electrodes that allow for the application of voltages to create electric fields that serve to prevent ion contact (and thus loss) during transmission. The electrodes include at a minimum a set to which RF voltages of opposite polarity, each ideally extending along the total conduit (i.e. strips), with adjacent strips having opposite polarity so as to create a pseudo potential preventing ions over a significant m/z range from closely approaching the surface. (The RF voltages etc are similar to those that can be used in SLIM devices.) The conduit can also have a second set of electrodes to which dynamic voltages are applied to the electrodes to create electric traveling waves (TW) to help move ions through the conduit, although other mechanisms such as a pressure drop or voltage gradient can also be used to urge ions through the conduit. The conduit can be highly flexible, allowing bending, etc., and of any length and width needed. It can, e.g., be used to move ions from one instrumental platform to another, such as from a separate ion mobility separation device to a mass spectrometer (MS). The ions can be moved in the device either without separation or with continued separation be proper selection of TW parameters, and work over a range of gas pressures, ideally at sub ambient pressures. The ion conduit can function as a stand alone ion mobility separator if provided with a mechanic for ion introduction to one end. Ion movement can be assisted or impeded using gas flow, or the voltages provided to the TW electrodes.
Methods for Magnetic Resonance Analysis Using Magic Angle Technique
Previous work has shown that it is possible to separate the susceptibility broadening in the 1H NMR metabolite spectrum obtained in a live mouse from the isotropic information, thus significantly increasing the spectral resolution. This was achieved using ultra-slow magic angle spinning of the animal combined with a modified phase-corrected magic angle turning (PHORMAT) pulse sequence. However, PHORMAT cannot be used for spatially selective spectroscopy. In this invention a modified sequence called LOCMAT (localized magic angle turning) is introduced that makes this possible. Proton LOCMAT spectra are shown for the liver and heart of a live mouse, while spinning the animal at a speed of 4 Hz in a 2 Tesla field. It was found that even in this relatively low field LOCMAT provided isotropic line widths that are a factor 4-10 times smaller than the ones obtained in a stationary animal, and that the susceptibility broadening of the heart metabolites shows unusual features not observed for a dead animal. Finally, the limitations of LOCMAT and possible ways to improve the technique are discussed. It is concluded that in vivo LOCMAT can significantly enhance the utility of NMR spectroscopy for biomedical research.