This paper suggests that minimum detectable dose (MDD) be used to describe the capability of bioassay programs for which intakes are expected to be rare. This allows expression of the capability in units that correspond directly to primary dose limits. The concept uses the well-established analytical statistic minimum detectable amount (MDA) as the starting point and assumes MDA detection at a prescribed time post intake. The resulting dose can then be used as an indication of the adequacy or capability of the program for demonstrating compliance with the performance criteria. MDDs can be readily tabulated or plotted to demonstrate the effectiveness of different types of monitoring programs. The inclusion of cost factors for bioassay measurements can allow optimisation.
Revised: January 5, 2009 |
Published: January 1, 2003
Citation
Carbaugh E.H. 2003.Minimum Detectable Dose as a Measure of Bioassay Programme Capability.Radiation Protection Dosimetry 105, no. No. 1-4:391-394.PNNL-SA-37060.