March 7, 2025
Journal Article
The impact of gas purity on observed reactivity with NO using inductively coupled plasma tandem mass spectrometry
Abstract
Interference removal in inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) is strongly dependent on the gas selected for use within the collision/reaction cell (CRC). While 99.999% gas purity is recommended for use, there has been little investigation into how pure a reaction gas needs to be and the effects that impurities may have on the resulting spectra. Here, lower purity nitric oxide (NO 99.5%) was evaluated for use in ICP-MS/MS with and without agas purifier prior to the CRC to reduce H2O impurities toPublished: March 7, 2025