Nanoceria has been shown to possess biomedical properties which have potential use in treatment of diseases caused by reactive oxygen species (ROS) like cancer. In the present work, stability and redox changes in nanoceria in the presence of polyhydroxyl groups such as glucose and dextran is reported. The effect of both acidic and basic medium on stability of nanoceria in the absence of buffer had been examined using UV-Visible spectroscopy and transmission electron microscopy. Experimental results showed that both dextran and glucose can extend the stability of nanoceria in basic medium without interfering with the redox chemistry. A comparison of aqueous and saccharides suspension in acid/base media undergoing redox transformation has been reported.
Revised: April 7, 2011 |
Published: November 22, 2007
Citation
Karakoti A.S., S.N. Kuchibhatla, K.S. Babu, and S. Seal. 2007.Direct Synthesis of Nanoceria in Aqueous Polyhydroxyl Solutions.Journal of Physical Chemistry C 111, no. 46:17232-17240.PNNL-SA-53941.doi:10.1021/jp076164k