A series of doubly-charged [4Fe4S] cluster ions, [Fe4S4X4](2-) (X = Cl, Br, I, and SCZHS), were produced in the gas phase by electrospray ionization and examined using collision-induced dissociation (CID) in a quadrupole ion trap. CID channels of each dianion were analyzed by MS/MS experiments at different collision energies. Two CID channels were observed for these dianions: symmetric fission and electron detachment. The most interesting observation is the symmetric fission of [Fe4S4X4](2-) into two identical daughter ions, [Fe2S2X2](-). The important role of the intramolecular coulomb repulsion in the symmetric fission was shown by comparing with CID of the singly-charged anions, [Fe4S4X4](-). Our gas-phase experiments suggest that solution phase conversions between [Fe4S4] and [Fe2S2] assemblies in proteins may also involve related fission chemistry with reactive [Fe2S2X2](-) intermediates. (C) 2003 Elsevier Science B.V All rights reserved.
Revised: March 2, 2004 |
Published: December 9, 2003
Citation
Yang X., X.B. Wang, and L. Wang. 2003.Collision-induced Symmetric Fission of Doubly-charged Cubelike [Fe4S4X4](2-) Clusters.International Journal of Mass Spectrometry 228, no. 2-3:797-805.PNNL-SA-39720.