June 1, 2001
Journal Article

Antimicrobial Efficacy of External Fixator Pins Coated with a Lipid Stabilized Hydroxyapatite/Chlorohexidine Complex to Prevent Pin Tract Infection in a Goat Model

Abstract

The Development of pin tract infections during external fixation of an open fracture can complicate or prevent the conversion to internal or intramedullary stabilization. Therefore, a pin that could prevent or delay the onset of an infection would be of clinical benefit in treating open fractures. The ideal pin would prevent infection butalso have no detrimental effects on the surrounding bone in which it is inserted. The purpose of our study was to evaluate the efficacy of hydroxyapatite and chlorhexidine coatings, alone and in combination, in delaying or preventing pin tract infection in an established Caprine model.

Revised: August 11, 2010 | Published: June 1, 2001

Citation

Dejong E., T.M. Deberardino, D.E. Brooks, B.J. Nelson, A.A. Campbell, C.R. Bottoni, and A.E. Pusateri, et al. 2001. Antimicrobial Efficacy of External Fixator Pins Coated with a Lipid Stabilized Hydroxyapatite/Chlorohexidine Complex to Prevent Pin Tract Infection in a Goat Model. Journal of Trauma - injury infection, and critical care 50, no. 6:1008-1014. PNWD-SA-5080.