PNNL

Dr. Kristie Oxford has worked for over 25 years in the detection, prevention, and characterization of infectious diseases. Her current research includes characterizing and interpreting host responses to viral infection using systems biology data, including transcriptomics using RNA sequencing and proteomics and lipidomics using high resolution mass spectrometry. Her team has studied host-virus interactions from thousands of samples representing over 12 human viruses to identify candidate biomolecules for medical intervention and/or mechanistic studies. In addition to this work, Dr. Oxford is a Lieutenant Colonel in the United States Air Force Reserve, supporting all branches of the military in public health and chemical and biological defense activities.

• PhD in Microbiology, University of California Davis
• BS in Zoology, North Carolina State University
• AS in Biotechnology, Solano Community College

• American Society for Virology
• American Society for Microbiology
• Air Force Association
• Reserve Officer’s Association

• Secretary of Energy Achievement Award for Department of Energy National Laboratories’ COVID-19 Clinical Testing Team, United States Department of Energy, 2021
• Outstanding Performance Award, Pacific Northwest National Laboratory, 2019
• NIH/NIAID Animal Models of Infectious Diseases Training Grant Award, 2008 - 2012
• Centers for Disease Control and Prevention/Association of Public Health Laboratory Emerging Infectious Disease Laboratory Training Fellowship, 2000 - 2002

2025

• Johnston G.P., F. Aydemir, H. Byun, E. De Wit, K.L. Oxford, J.E. Kyle, and J.E. McDermott, et al. 2025. "Multi-platform 'omics' analysis of Nipah virus infection reveals viral glycoprotein modulation of mitochondria." Cell Reports 44, no. 3:115411. PNNL-SA-209082. doi:10.1016/j.celrep.2025.115411

2023

• Leiser O.P., D.L. Auberry, E. Bakker, W.B. Chrisler, K.M. Engbrecht, H.E. Engelmann, and S.J. Fansler, et al. 2023. "Insights from a workplace SARS-CoV-2 specimen collection program, with genomes placed into global sequence phylogeny." PLoS One 18, no. 4:Art. No. e0285042. PNNL-SA-179220. doi:10.1371/journal.pone.0285042

2021

• Ostaszewski M., A. Niarakis, A. Mazein, I. Kuperstein, R. Phair, A. Orta-Resendiz, and V. Singh, et al. 2021. "COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms." Molecular Systems Biology 17, no. 10:e10387. PNNL-SA-168044. doi:10.15252/msb.202110387
• Oxford K.L., J.D. Zucker, J.R. Teuton, and M. Ostaszewski. 2021. "COVID19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms." Molecular Systems Biology 17, no. 10:e10387. PNNL-SA-157722. doi:10.15252/msb.202110387
• Zucker J.D., K. Paneri, S. Mohammad-Taheri, S. Bhargava, P. Kolambkar, C. Bakker, and J.R. Teuton, et al. 2021. "Leveraging Structured Biological Knowledge for Counterfactual Inference: A Case Study of Viral Pathogenesis." IEEE Transactions on Big Data 7, no. 1:25-37. PNNL-SA-154544. doi:10.1109/TBDATA.2021.3050680

2019

• Hutchison J.R., S.M. Brooks, Z.C. Kennedy, T.R. Pope, B. Kaiser, K.D. Victry, and C.L. Warner, et al. 2019. "Polysaccharide-based liquid storage and transport media for non-refrigerated preservation of bacterial pathogens." PLoS One 14, no. 9:e0221831. PNNL-SA-142625. doi:10.1371/journal.pone.0221831
• McClure R.S., J.P. Wendler, J.N. Adkins, J.A. Swanstrom, R. Baric, B. Kaiser, and K.L. Oxford, et al. 2019. "Unified Feature Association Networks through Integration of Transcriptomic and Proteomic Data." PLoS Computational Biology 15, no. 9:e1007241. PNNL-SA-137420. doi:10.1371/journal.pcbi.1007241

2016

• Oxford K.L., J.P. Wendler, J.E. McDermott, R.A. White, J.D. Powell, J.M. Jacobs, and J.N. Adkins, et al. 2016. "The Landscape of Viral Proteomics and Its Potential to Impact Human Health." Expert Review of Proteomics 13, no. 6:579-591. PNNL-SA-116259. doi:10.1080/14789450.2016.1184091