Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

Scientists at PNNL have published a new article that focuses on understanding the composition, dynamics, and deployment of beneficial soil microbiomes to get the most out of soil.

A team of researchers from PNNL provided technical knowledge and support to test a suite of techniques that detect genetically modified bacteria, viruses, and cells.

PNNL’s Nick Ward has been honored with the American Geophysical Union’s Thomas Hilker Early Career Award.

The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.

SAGE is a high-efficiency genome integration strategy for bacteria that makes the stable introduction of new traits simple for newly discovered microbes.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

Diefenderfer, Earth scientist who focuses on coastal ecosystems at PNNL, recently published “Ten Years of Gulf Coast Ecosystem Restoration Projects Since the Deepwater Horizon Oil Spill,” a cover article.

TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.

The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.

ICON science is a Department of Energy-developed framework to enhance scientific outcomes via more intentional design of research efforts across all domains of science.

An analysis of land use in watersheds that supply drinking water to over a hundred United States cities identified a wide range of exposure to potential contamination.

PNNL scientists are taking part in a Department of Energy climate science field campaign in the Rocky Mountains of Colorado.

COMPASS points to understanding nature’s transition zones—areas that can be dry land at times and under water at others.