PNNL researchers are opening up a new front in the fight to stop viral pathogens, protecting people against multiple viruses.

Capturing protein structural changes in host cells exposes vulnerabilities exploited by viruses to hijack cellular machinery.

Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

From producing radioisotope generators to recovering source materials, researchers are meeting a growing need for medical radioisotopes.

PNNL researchers continue to deliver high-quality, high-impact research on radioactive waste and nuclear materials management, earning “Papers of Note” and “Superior Paper” awards.

PNNL researchers showcased subsurface sampling and remediation expertise at the 2025 Federal Remediation Technologies Roundtable.

This study used historical data, remote sensing, and aquatic sensors to measure how far wildfire impacts propagated through the watershed after the 2022 Hermit’s Peak/Calf Canyon fire, New Mexico’s largest wildfire in history.

The Coastal Observations, Mechanisms, and Predictions Across Systems and Scales: Field, Measurements, and Experiments project established a network of observational field sites across Chesapeake Bay and western Lake Erie.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

A new study led by PNNL researcher TC Chakraborty provides some answers about how irrigated agricultural land near cities affects urban heat stress.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

RemPlex and IAEA convene international leaders to tackle recruitment and retention in complex environmental cleanup efforts.

CACTUS provides AI-powered cheminformatics for autonomous science.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Scientists are using artificial intelligence and powerful computing to sculpt new molecules in an effort to treat disease.

PNNL chief data scientist Lauren Charles participated in a science-focused panel linked to the 79th session of the United Nations General Assembly.

Controlling the nanostructure of silk fibroin—a protein found in silk—is a key step toward designing and fabricating electronics that leverage the material’s promising mechanical, optical and biocompatible properties.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.