Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.

Input from humans helps when deciding whether to trust the recommendations or decisions of a machine-learning system.

PNNL’s software tool brings together artificial intelligence and satellite imagery to help responders assess damage and take action.

Recovery Simulator and Analysis tool further strengthens PNNL’s short-term resilience planning efforts for Puerto Rico.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

New research findings published in Science Advances (November 2022), help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

PNNL chemist Ying Zhu was honored as one of the top 40 researchers under the age of 40 in analytical science by The Analytical Scientist.

TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.

The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.

PNNL researchers developed a new model to help power system operators and planners better evaluate how grid-forming, inverter-based resources could affect the system stability.

PNNL scientists publish paper and host workshops to share threat-agnostic vision for biodefense.

The nested nanoPOTS chip is the next generation of technology developed at PNNL to prepare single cells for proteomics.

A study of Middle East Respiratory Syndrome has identified a compound that shows potential in easing the symptoms of coronavirus infections.

Mary Lancaster, epidemiologist and data scientist, co-authored a chapter on cyberbiosecurity for the NATO Science for Peace and Security book series.