Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Three PNNL researchers will receive five continuous years of funding for projects through highly competitive DOE Early Career Research Program awards.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

New research sheds light on the biomolecular dangers of night shift work.

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

A streamlined informatics workflow that automatically processes complex data and provides the locations of double bonds in lipids.

Hi-C metagenomics-informed phage-host infection networks detected in soil pre- and post-drying.

Metabolomics analysis revealed differences in metabolome profiles for two distinct modes of fungal wood decay.

A detailed snapshot of proteins by PNNL scientists marks a big step toward a diagnostic blood test for a deadly form of liver disease.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.

The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.

Data from increasingly complex mass spectrometry instruments met with adaptable data analysis solution.