Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.

PNNL’s patented Shear Assisted Processing and Extrusion (ShAPE™) technique is an advanced manufacturing technology that enables better-performing materials and components while offering opportunities to reduce costs and energy consumption.

Scott Whalen, a chief scientist in the Applied Materials and Manufacturing group at PNNL, has been named 2023 PNNL Inventor of the Year

The next-generation ShAPE machine has arrived at PNNL, where it will help prove the mettle of the ShAPE extrusion technique. ShAPE 2 is designed to allow researchers to produce larger, more complex extrusions.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

The Department of Energy’s Vehicle Technologies Office recently issued two awards to researchers at PNNL for their contributions to areas that are crucial for the expansion of electric vehicles.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

The PNNL-patented ShAPE™ manufacturing process produces high-strength aluminum vehicle parts that lower costs and are more environmentally friendly.

PNNL senior materials scientist Keerti Kappagantula has been named to the 2023 Nominating Committee of ASM International.

A detailed snapshot of proteins by PNNL scientists marks a big step toward a diagnostic blood test for a deadly form of liver disease.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

Research published in Journal of Manufacturing Processes demonstrates innovative single-step method to manufacture oxide dispersion strengthened copper materials from powder.

Multidisciplinary teams from research and industry are brought together using management systems developed by a team of software engineers at PNNL.

A new extrusion process eliminates pre-heating to provide significant energy savings during production of extruded aluminum alloys.

The first-ever simulation of aluminum conductivity offers a recipe for an inexpensive, lightweight alternative to copper.

Road tripping? PNNL’s researchers driving science and technology for clean, efficient and convenient transportation.

Study highlights microbiome’s role in regulating xenobiotic metabolism.