Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

Controlling the nanostructure of silk fibroin—a protein found in silk—is a key step toward designing and fabricating electronics that leverage the material’s promising mechanical, optical and biocompatible properties.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

New research sheds light on the biomolecular dangers of night shift work.

Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for both sexes.

Scientists have learned more about how to protect the insulin-producing cells that die in patients with Type 1 diabetes.

PNNL researchers helped identify a fragment from the SARS-CoV-2 virus that spurs severe illness.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

Scientists have opened a new view into the workings of the central nervous system, finding a diverse set of important molecules.

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

Exploring why some brains are more resilient to the impact of Alzheimer’s disease could lead to improved diagnoses, treatment and prevention.

A detailed snapshot of proteins by PNNL scientists marks a big step toward a diagnostic blood test for a deadly form of liver disease.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

Interns dive into important research that addresses national needs.

The Washington State Academy of Sciences added six people from PNNL to its 2022 class of inductees.

The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.

Studying MERS-CoV may lead to better treatments for a host of respiratory illnesses, including the many variants of COVID-19.