Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

Testing the assumption that different future socio-economic development patterns, which result in different land-use changes, can be paired with different future climate outcomes for risk assessments in a multi-model framework.

Incorporating spatially explicit land characteristics in a global model illustrates the complex effects of applying uniform regional protection assumptions in a global analysis.

Unveiling diverse scenarios and implications for water resource management in a rapidly changing world.

Quantifying the long-term destination of anthropogenic emissions and robustness of global carbon sinks.

New study identifies crucial factors for more accurate hydrological predictions in the Community Land Model version 5.

Groundwater modeling of irrigation return flow dynamics is important for improving estimates of water availability.

A review describes the latest techniques for simulating hydropower at large scales to inform power grid planning and operations.

Hydropower generation estimated using water proxy data leads to a revision of the nation’s historical seasonal hydropower output.

COVID-19 infections at PNNL early in the pandemic were caused by a wide variety of viral sequences, according to a new analysis by Laboratory researchers.

A new model uses machine learning to project electricity loads across the United States.

Future global warming-induced changes to watershed and coastal processes can significantly affect the magnitude of fluvial-coastal compound flooding.

Mesoscale convective systems that are clustered in time and space have broader impacts on flooding than individual systems.

Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.

A scenario approach was used to explore the potential future role of hydropower around the globe considering the multisectoral dynamics of regional energy systems and basin-specific water resources.

A new report, based on a community workshop and literature review, summarizes some of the biggest challenges in understanding and modeling Earth system and human–Earth system dynamics in the Puget Sound region of Washington State.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Building new climate outcome scenarios by stitching together pieces of existing ones.

Researchers found that specific landscape metrics consistently outperform traditional population downscaling methods.

A systematic, multiple scenario approach was used to analyze the compounding impacts of demands for land for biofuels with increased land scarcity under a diverse set of uncertainties.