PNNL

We are proud to announce the inaugural Predictive Phenomics conference organized by Pacific Northwest National Laboratory (PNNL) in Richland, WA. The theme of the 2025 conference is Advancing Molecular Science for the Characterization and Manipulation of the Phenome. 

The conference will consist of keynotes, invited talks, poster sessions, PNNL tours, and a forum for scientists to present research on approaches to study the molecular basis of biological function with a vision to better understand and predict how genomes interact with their environment to produce phenomes. We expect up to ~200 attendees who specialize in pushing predictive phenomics forward via state-of-the-art technology development and science.

Registration now open!

Register by April 22 to attend the inaugural Predictive Phenomics conference.

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Conference Topics

View the Conference Agenda

• Deciphering Molecular Interactions: Uncovering the intricacies of molecular interactions that underpin biological function.
• Multi-omics Characterization of Biological Samples: Integrative analysis of genomic, transcriptomic, proteomic, and metabolomic data.
• Spatial and Single-Cell Biology: Techniques and discoveries in spatial and single-cell biology that reveal the complexity of phenotypes.
• Identification of Novel Molecular Species: Discovery of new molecular entities, including proteoforms, post-translational modifications, and small molecules.
• Molecular Characterization of Phenotypes: Approaches to define and describe phenotypes at the molecular level.
• Integrating Molecular Data to Predict Phenotype: Leveraging multi-omics data for predictive modeling of phenotypes.
• Controlling and Engineering Phenotypes: Advances in the manipulation and engineering of phenotypes.
• Understanding the Dynamics of Phenotypes: Insights into the temporal dynamics and variability of phenotypes.

Keynote Speakers

Dr Richard D. Smith

One Person’s Path and Personal Perspective on the History of Mass Spectrometry for Molecular Measurements at PNNL

Tuesday, April 29, 2025 (8:45 AM, Pacific)

Biography: Dr. Smith retired in 2024 after serving as a Battelle Fellow and Chief Scientist in the Biological Sciences Division at Pacific Northwest National Laboratory (PNNL). His research focused on the development of advanced analytical methods and instrumentation, particularly in the areas of high-resolution separations and mass spectrometry, with applications spanning biological and biomedical research. Dr. Smith also led PNNL's Proteomic and Pan-omic Research and served as Director of the NIH Research Resource for Integrative Biology. He authored or co-authored nearly 1,200 peer-reviewed journal articles and holds 80 patents. Dr. Smith's many accolades include twelve R&D 100 Awards, the R&D Magazine 2010 Scientist of the Year, the 2013 ASMS Distinguished Contribution Award, the HUPO Discovery Award for Proteomic Sciences (2009), election as a Fellow of the American Association for the Advancement of Science (2007), and the American Chemical Society Award for Analytical Chemistry (2003).

Dr. Katrina Waters

Predictive Phenomics: The Next Revolution in Life Sciences

Tuesday, April 30, 2025 (8:45 AM, Pacific)

Biography: Dr. Katrina Waters is a Laboratory Fellow and Chief Scientist for biological sciences research at the Pacific Northwest National Laboratory (PNNL). Her research interests are focused at the intersection of environmental exposures and infectious disease on human health. With more than 150 publications, she has built a national and international reputation through her leadership and innovation in data integration and interpretation for systems toxicology data as well as high-throughput screening data. Her programs include the study of health effects of chemicals at Superfund sites and personal environmental exposure assessment for epidemiological studies in disadvantaged communities. She is currently Deputy Director of the Oregon State University (OSU) – PNNL Superfund Research Center. Recently, she completed a Department of Energy research program focused on airborne and environmental transmission of COVID-19.  She has also led numerous research efforts in computational modeling, bioinformatics, and data management for aNational Institute of Allergy and Infectious Diseases (NIAID) Center for Predictive Modeling of Infectious Diseases and a Department of Homeland Security program for Predictive Modeling of Viral Infections. Dr. Waters holds joint faculty appointments with OSU and the University of Washington.

Invited Speakers

(alphabetical order by last name)

• Kristin Burnum-Johnson – Science Group Leader, Functional & Systems Biology, Pacific Northwest National Laboratory
• Andrew Emili – Professor, Oregon Health & Science University
• Lan Huang – Professor, Physiology and Biophysics, University of California
• Davinia Salvachua Rodriguez – Group Research Manager, Biological Sciences, National Renewable Energy Laboratory
• Yinjie Tang – Energy, Environmental & Chemical Engineering Professor, McKelvey School of Engineering
• Hans Van Dongen – Professor, Washington State University
• Cranos Williams – Goodnight Distinguished Professor of Agricultural Analytics, NC State University
• Vicki Wysocki – Ohio Eminent Scholar, The Ohio State University

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