Pacific Northwest National Laboratory (PNNL) has been requested by the U.S. Nuclear Regulatory Commission to evaluate the reactivity initiated accident (RIA) tests that have recently been performed in the Nuclear Safety Research Reactor (NSRR) and CABRI (French research reactor) on uranium dioxide (UO2) and mixed uranium and plutonium dioxide (MOX) fuels, and to propose pellet-cladding mechanical interaction (PCMI) failure thresholds for RIA events. This report discusses how PNNL developed PCMI failure thresholds for RIA based on least squares (LSQ) regression fits to the RIA test data from cold-worked stress relief annealed (CWSRA) and recrystallized annealed (RXA) cladding alloys under pressurized water reactor (PWR) hot zero power (HZP) conditions and boiling water reactor (BWR) cold zero power (CZP) conditions.