June 24, 2008
Journal Article

Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel Nudix hydrolase with a preference for cytosine (deoxy) ribonucleoside 5'-di- and triphosphates

Abstract

The Deinococcus radiodurans Nudix hydrolase DR0079 was assayed for activity towards a wide variety of substrates and observed to have a marked specificity for cytosine ribonucleoside 5’-diphosphate (CDP) and cytosine ribonucleoside 5’-triphosphate (CTP) with a slight preference for CDP. The next most specific substrates, with a relative activity of

Revised: August 6, 2008 | Published: June 24, 2008

Citation

Buchko G.W., O. Litvinova, H. Robinson, A.F. Yakunin, and M.A. Kennedy. 2008. Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel Nudix hydrolase with a preference for cytosine (deoxy) ribonucleoside 5'-di- and triphosphates. Biochemistry 47, no. 25:6571-82. PNNL-SA-58409.