December 1, 2012
Journal Article

Development of a Proteoliposome Model to Probe Transmembrane Electron-Transfer Reactions

Abstract

The mineral respiring bacterium Shewanella oneidensis uses a protein complex, MtrCAB, composed of two decaheme cytochromes brought together inside a transmembrane porin to transport electrons across the outer membrane to a variety of mineral-based electron acceptors. A proteoliposome system has been developed that contains methyl viologen (MV) as an internalised electron acceptor and valinomycin (V) as a membrane associated cation exchanger. These proteoliposomes can be used as a model system to investigate MtrCAB function.

Revised: August 12, 2014 | Published: December 1, 2012

Citation

White G.F., Z. Shi, L. Shi, A. Dohnalkova, J.K. Fredrickson, J.M. Zachara, and J.N. Butt, et al. 2012. Development of a Proteoliposome Model to Probe Transmembrane Electron-Transfer Reactions. Biochemical Society: Transactions 40, no. 6:1257-1260. PNNL-SA-88014. doi:10.1042/BST20120116