September 26, 2005
Conference Paper

A Biomimetic Approach to Discrimination Between Sequential and Concerted Models for the Oxidation of Ubiquinol at the Qo­ site of the Cyt bc1 Complex

Abstract

The cytochrome bc complexes function as quinol:cytochrome c oxidoreductases in the energy conserving membranes of nearly all organisms, where they couple the oxidation of a quinol substrate (QH2) to the pumping of protons across the bioenergetic membrane, resulting in the establishment of a proton motive force, which is used to drive the (C)F0/(C)F1 ATP synthase (Trumpower and Gennis 1994). Among the variety of biological quinols characterized, ubiquinol is the substrate used by most bc-type complexes, and its reactions are of great interest concerning diseases related to oxidative stress and the fundamentals of biological energy transduction.

Revised: April 7, 2011 | Published: September 26, 2005

Citation

Cape J.L., I.P. Forquer, M.K. Bowman, and D.M. Kramer. 2005. A Biomimetic Approach to Discrimination Between Sequential and Concerted Models for the Oxidation of Ubiquinol at the Qo­ site of the Cyt bc1 Complex. In Photosynthesis : fundamental aspects to global perspectives : proceedings of the 13th International Congress on Photosynthesis, Montreal 2004, 1095-1097. Lawrence, Kansas:Alliance Communications Group. PNNL-SA-45294.