Dilute aqueous solutions of the calcium and sodium salts of -D-isosaccharinate (ISA) have been analyzed by 13C and 1H NMR spectroscopy. The positions of the six 13C ISA NMR lines show a pH dependence that can be used to infer that the most acidic proton is the one associated with the carboxylate group, with a log k0 of -3.27 - -3.36 for the reaction H(ISA) H+ K ISA-.
Revised: June 29, 2011 |
Published: August 1, 2003
Citation
Cho H.M., D. Rai, N.J. Hess, Y. Xia, and L. Rao. 2003.Acidity and Structure of Isosaccharinate in Aqueous Solution: A Nuclear Magnetic Resonance Study.Journal of Solution Chemistry 32, no. 8:691-702.PNNL-SA-38699.