The Isotope Program at PNNL supports scientific advances in the production and use of radioisotopes for research, medicine, and industrial applications.

PNNL administers two research buoys for the U.S. Department of Energy that allows collection of wind meteorological and oceanographic data off the nation's coasts.

The RD2C laboratory-directed research initiative seeks to develop resilient, adaptive, and intelligent sensing and control algorithms through the observational understanding and characterization of CPSs under adverse conditions.