PNNL

Poki Tse is a chemist focusing on developing online monitoring tools for the nuclear industry and clean energy development. She works in several projects to design and test new flow cells used to optimize the real-time measurement of analytes in used nuclear fuel reprocessing and other clean energy-related processes. She also works on combining optical spectroscopies with a chemical data science algorithm called chemometric analysis to quickly quantify solution conditions and analyte concentrations in used nuclear fuel reprocessing and nuclear waste streams that can help to improve efficiency, maintain accountability, and enhance safety.

• Chemometrics
• Electrochemistry and spectroelectrochemistry
• MATLAB
• Optical spectroscopy
• Online monitoring
• Analytical chemistry

• Doctor of Philosophy, Applied Chemistry, Colorado School of Mines
• Bachelor of Science, Chemistry, University of Washington
• Associate of Science, 2 Year AA or AS degree, Olympic College

• Member, American Chemical Society

• Roy G. Post Scholarship, The Roy G. Post Foundation, WM Symposia, 2022
• Award for Distinguished Research in Chemistry, Department of Chemistry, University of Washington, 2017
• Clara and Edward Degering Tuition Scholarship, Department of Chemistry, University of Washington, 2016
• Mary Gates Research Scholarship, University of Washington, 2016
• 2016 Battelle Scholar Awardee

• P. Tse, P. Guerrero-Almaraz, J.M. Rakos, Q. Wang, C.V. Subban,C.A. Burns, S.A. Bryan, A.M. Lines. Optimizing the time resolution of automated data analysis of fluorescence of highly complex mixed REE solutions and actual feedstocks, Submitted.
• J.M. Rakos, P. Tse, A.F. Espley, P. Guerrero-Almaraz, Q. Wang, C.V. Subban, S.A. Bryan, A.M. Lines. Fluorescence Signatures of Rare Earth Metals during Precipitation in Various Conditions, Langmuir 2026, 42 (25), 18151-18157.
• H.M. Felmy, N.T.C. Boily, A. Schafer Medina, P. Tse, A.M. Westesen, J.M.Bello, S.A. Bryan, A.M. Lines. Raman Spectroscopic In Situ Monitoring of Highly Turbid Media, Analytical Chemistry 2026, 98 (11), 8594-8604.
• H.M. Felmy, P.Tse, P. Guerrero-Almaraz, S.A. Bryan, A.M. Lines. Demonstration of Optical Spectroscopic Flow Cell Design for Molten Salt Reactor Off-Gas Streams. 2025, PNNL-38277.
• N.P. Bessen, P. Tse, T. Serrano, H.E. Lackey, H.M. Felmy, G.L. Nelson, A.F. Espley, S.M. Potter, R.R. Rodrigues, A.H. Parekh, G.J. Lumetta, B.N. Seiner, S.A. Bryan, A.M. Lines.Automated pH Monitoring and Control of TALSPEAK and Advanced TALSPEAK Processes, Analytical Chemistry 2025, 97 (35), 19019-19027. 
• T. Serrano, A.F. Espley, S.M. Potter, K.A. Ross, P. Tse, N.P. Bessen, H.M. Felmy, H.E. Lackey, J.R. Allred, B.N. Seiner, G.J. Lumetta, G.L. Nelson, S.A. Bryan, A.M. Lines. Real-Time Automated pH Control within Batch Processes Relying on Raman pH Measurement, ACS Omega 2025, 10 (18), 18238-18250.
• P. Tse, A.F. Espley, J.M. Rakos, Q. Wang, C.V. Subban, S.A. Bryan, A.M. Lines. Developing Fluorescence-Based Sensors to Support Rare Earth Element Separation, ACS Sensors 2025, 10 (7), 4974-4982.
• P. Tse, N.P. Bessen, A.F. Espley, H.M. Felmy, H.E. Lackey, R.R. Rodrigues, A.H. Parekh, S.M. Potter, G.L. Nelson, J.R. Allred, G.B. Hall, B.N. Seiner, G.J. Lumetta, S.A. Bryan, A.M. Lines. Spectroscopic Online Monitoring: Using a Multi-Track Visible Spectrometer to Facilitate a Mass Balance Study in a Simulated TALSPEAK Process, ACS Omega 2025, 10 (12), 11796-11805.
• N.P. Bessen, D. Boglaienko, D.D. Mayberry, H.M. Felmy, P. Tse, R.R. Rodrigues, and G.J. Lumetta, et al. Direct Extraction: Engineered Test Apparatus. 2024, PNNL-35808.
• H.M. Felmy, A. Schafer Medina, N.T.C. Boily, W. Brownell, P. Tse, S.A. Bryan, A.M. Lines . Deployment of In-Line Sampling in Tank Farms. 2024, PNNL-36616.
• P. Tse, N.P. Bessen, G.B. Hall, B.N. Seiner, G.J. Lumetta, S.A. Bryan, A.M. Lines. A Review of Online Monitoring within Used Nuclear Fuel Recycling Processes, Solvent Extraction and Ion Exchange. 2024, 42 (5), 347-380.
• P. Tse, N.P. Bessen, S. Galley, S.A. Bryan, A. Lines, J. Shafer. Electrochemical Oxidation and Speciation of Lanthanides in Potassium Carbonate Solution, J. Electrochem. Soc. 2022.
• P. Tse, J.C. Shafer, S.A. Bryan, G.L. Nelson, A.M. Lines. Measuring Nd(III) Solution Concentration in the Presence of Interfering Er(III) and Cu(II) Ions: A Partial Least Squares Analysis of UV-Vis Spectra. Appl. Spectrosc. 2021, 76 (2), 173–183.
• P. Tse,  J. Shafer, S.A. Bryan, A.M. Lines. Quantification of Raman Interfereing Polyoxoanions for Process Analysis: Comparison of Different Chemometric Models and a Demonstration on Real Hanford Waste. Environ. Sci. Technol. 2021, 55 (19), 12943–12950.
• A.M. Lines, H.M. Felmy, P. Tse, K.M. Denslow, M.S. Fountain, M.J. Minette, I. Wheeler, S.A. Bryan. Real-time Sampling for Process Control and Validation: Leveraging On-Line Monitroing Advacnes in Low-Level Waste to High-Level Waste Processing at Hanford, in: WM 2021, 2021.
• P. Tse, S.A. Bryan, N.P. Bessen, A.M. Lines, J.C. Shafer. Review of on-line and near real-time spectroscopic monitoring of processes relevant to nuclear material management. Anal. Chim. Acta. 2020, 1107, 1–13.
• A.M. Lines, S.A. Bryan, P. Tse, K.M. Denslow, M.S. Fountain, K.D. Boomer, D.N. Stewart. Application of On-Line Monitoring and Real-Time Characterization of Low Level Waste Samples from Hanford Tanks, in: WM 2020, Phoenix, 2020.
• S.A. Bryan, K.M. Denslow, T.G. Levitskaia, J.M. Schwantes, A.M. Lines, H.M. Felmy, and P. Tse, et al. Online Monitoring Capabilites for Hanford. 2019.
• A.M. Lines, P. Tse, H.M. Felmy, J.M. Wilson, J. Shafer, K.M. Denslow, A.N. Still, C. King, S.A. Bryan. Online, Real-Time Analysis of Highly Complex Processing Streams: Quantification of Analytes in Hanford Tank Sample, Ind. Eng. Chem. Res. 2019, 58 (47), 21194–21200.
• A.M. Lines, S.A. Bryan, P. Tse, K.M. Denslow, M.S. Fountain, K.D. Boomer, A.J. Kim, D.N. Stewart. On-Line Monitoring and Real-Time Characterization of Low-Level Waste and Off-Gas Condensate Samples Using Raman Spectroscopy, in: WM 2019, Phoenix, 2019.
• S.A. Bryan, A.M. Lines, P. Tse, H.M. Felmy, and K.M. Denslow. Demonstration of On-line Monitoring of AP-105 Tank Waste Sample with Raman Spectroscopy. 2019.