Lab Fellow, Chief Science Officer
Lab Fellow, Chief Science Officer


Justin Teeguarden is a PNNL Lab Fellow and the chief science officer for the Environmental Molecular Sciences Laboratory (EMSL) User Program. With over 20 years of scientific leadership as a computational and experimental scientist, Teeguarden leads EMSL's strategic science planning and internal R&D initiatives. He currently serves as vice-chair of the U.S. Environmental Protection Agency’s (EPA) Board of Scientific Counselors Homeland Security Subcommittee, as PNNL’s representative to the Indo Pacific Research Alliance for Military Medicine, and he holds a joint appointment with the Department of Environmental and Molecular Toxicology at Oregon State University (OSU) where he is the principal investigator on the PNNL-OSU National Institutes of Health Superfund research program. Teeguarden has served on multiple National Academy of Sciences (NAS) Committees, and his various roles are a result of extensive experience in computational modeling, toxicology, and exposure science. 

Teeguarden’s technical accomplishments fall into three major thematic areas:

  • Development and regulatory application of computational models and frameworks for simulating the fate and transport of chemicals (drugs, toxicants, metals) and their interaction with biological receptor systems in humans;
  • Development of the operative theories, models, and paradigms (experimental and computational) used by the field of toxicology to measure, model, and predict the fate of nanoparticles in in vitro cell culture systems used for toxicity screening; and
  • Quantitative and experimental approaches to measuring the contribution of environmental and endogenous estrogens in humans by integrating clinical, environmental, and computational exposure assessment methods.


  • PhD in Toxicology, University of Wisconsin-Madison, 1999
  • BS in Biochemistry, University of California, Davis, 1990

Affiliations and Professional Service

  • Chair, NAS Committee to review the U.S. Department of Defense physiologically based pharmacokinetic model for establishing occupational exposure limits for lead exposure (2019 – 2020) 

  • Homeland Security Subcommittee, U.S. EPA Board of Scientific Councilors (2018 – Present) 

  • Editorial Board, Computational Toxicology (2016 – Present) 

  • Member, NAS Committee on Incorporating 21st Century Science into Risk Based Decisions (2015 – 2017) 

  • Editorial Board, Journal of Exposure Science and Environmental Epidemiology (2014 – Present) 

  • Committee on Contemporary Concepts in Toxicology, Society of Toxicology (SOT) (2012) 

  • Member, NAS Committee on Exposure Science in the 21st Century (2011 – 2012) 

  • President, Nanotoxicology Specialty Section, SOT (2011 – 2012) 

  • Associate Editor, Nanotoxicology (2011 – Present) 

  • Board of Scientific Counselors, National Toxicology Program (2009 – 2011) 

  • Councilor, Biological Modeling Specialty Section, SOT (2008 – 2009) 

  • Chair, Dose-Response Specialty Group, Society of Risk Analysis (2004 – 2006) 

  • Diplomate, American Board of Toxicology (2002 – Present) 

  • Vice-Chair, Board of Scientific Counselors Homeland Security Subcommittee, U.S. EPA 

  • Representative, Indo Pacific Research Alliance for Military Medicine 

  • Joint Appointment, Department of Environmental and Molecular Toxicology, OSU 

  • National Academies of Sciences committees 

  • Secretary, Research Triangle Chapter, Society of Risk Analysis (2000 – 2001) 



  • Colby S.M., D.G. Thomas, J. Nunez, D.J. Baxter, K.R. Glaesemann, J.M. Brown, and M.A. Pirrung, et al. 2019. "ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries." Analytical Chemistry 91, no. 7:4346-4356. PNNL-SA-138476. doi:10.1021/acs.analchem.8b04567
  • Pande P., S.C. Fleck, N.C. Twaddle, M.I. Churchwell, D.R. Doerge, and J.G. Teeguarden. 2019. "Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women II: Total estrogenicity calculations accounting for competitive protein and receptor binding and potency." Food and Chemical Toxicology 125. PNNL-ACT-SA-10390. doi:10.1016/j.fct.2018.12.013
  • Septiadi D., L. Rodriguez-Lorenzon, S. Balog, M. Spuch-Calvar, G. Spiaggia, P. Taladriz-Blanco, and H. Barosova, et al. 2019. "Quantification of Carbon Nanotube Doses in Adherent Cell Culture Assays Using UV-VIS-NIR Spectroscopy." Nanomaterials 9, no. 12:1765. PNNL-SA-150718. doi:10.3390/nano9121765
  • Thrall B.D., V.K. Kodali, S.J. Skerret, S.J. Skerret, D.G. Thomas, C. Frevert, and J.G. Pounds, et al. 2019. "Modulation of susceptibility to lung bacterial infection by engineered nanomaterials: In vitro and in vivo correspondence based on macrophage phagocytic function." NanoImpact 14. PNNL-SA-128523. doi:10.1016/j.impact.2019.100155


  • Fantke P., L.L. Aylward, J. Bare, W. Chiu, R. Dodson, R. Dwyer, and A. Ernstoff, et al. 2018. "Advancements in Life Cycle Human Exposure and Toxicity Characterization." Environmental Health Perspectives 126, no. 12:CID: 125001. PNNL-SA-148788. doi:10.1289/EHP3871
  • Fleck S.C., N.C. Twaddle, M.I. Churchwell, D.R. Doerge, P. Pande, and J.G. Teeguarden. 2018. "Comparative Extrogenicity of Endogenous, Environmental and Dietary Estrogens in Pregnant Women I: Serum Levels, Variability and the Basis for Urinary Biomonitoring of Serum Estrogenicity." Food and Chemical Toxicology 115. PNNL-ACT-SA-10289. doi:10.1016/j.fct.2018.03.017
  • Geier M., D. Minick, L. Truong, S.C. Tilton, P. Pande, K. Anderson, and J.G. Teeguarden, et al. 2018. "Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish." Toxicology and Applied Pharmacology 354. PNNL-SA-144343. doi:10.1016/j.taap.2018.03.029
  • Smith J.N., D.G. Thomas, H.D. Jolley, V.K. Kodali, M.H. Littke, P. Munusamy, and D.R. Baer, et al. 2018. "All that is Silver is not Toxic: Silver Ion and Particle Kinetics Reveals the Role of Silver Ion Aging and Dosimetry on the Toxicity of Silver Nanoparticles." Particle and Fibre Toxicology 15. PNNL-SA-135829. doi:10.1186/s12989-018-0283-z
  • Tan Y., J.A. Leonard, S. Edwards, J.G. Teeguarden, and P. Egeghy. 2018. "Refining the aggregate exposure pathway." Environmental Science: Processes & Impacts 20, no. 3:428-436. PNNL-SA-137436. doi:10.1039/C8EM00018B
  • Thomas D.G., J.N. Smith, B.D. Thrall, D.R. Baer, H.D. Jolley, P. Munusamy, and V.K. Kodali, et al. 2018. "ISD3: A Particokinetic Model for Predicting the Combined Effects of Particle Sedimentation, Diffusion and Dissolution on Cellular Dosimetry for In Vitro Systems." Particle and Fibre Toxicology 15. PNNL-SA-125563. doi:10.1186/s12989-018-0243-7
  • Yesiltepe Y., J. Nunez, S.M. Colby, D.G. Thomas, M.I. Borkum, P.N. Reardon, and N.M. Washton, et al. 2018. "An automated framework for NMR chemical shift calculations of small organic molecules." Journal of Cheminformatics 10. PNNL-SA-137588. doi:10.1186/s13321-018-0305-8


  • Davie-Martin C.L., K.G. Stratton, J.G. Teeguarden, K.M. Waters, and S.L. Massey Simonich. 2017. "Implications of bioremediation of polycyclic aromatic hydrocarbon-contaminated soils for human health and cancer risk." Environmental Science & Technology 51, no. 17:9458-9468. PNNL-SA-122323. doi:10.1021/acs.est.7b02956
  • Knecht A., L. Truong, S.W. Marvel, D. Reif, A. Garcia, C. Lu, and M. Simonich, et al. 2017. "Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish." Toxicology and Applied Pharmacology 329. PNNL-SA-127160. doi:10.1016/j.taap.2017.05.033
  • Ma J., C.P. Casey, X. Zheng, Y.M. Ibrahim, C.S. Wilkins, R.S. Renslow, and D.G. Thomas, et al. 2017. "PIXiE: An Algorithm for Automated Ion Mobility Arrival Time Extraction and Collision Cross Section Calculation using Global Data Association." Bioinformatics 33, no. 17:2715-2722. PNNL-SA-122828. doi:10.1093/bioinformatics/btx305
  • Metz T.O., E.M. Baker, E.L. Schymanski, R.S. Renslow, D.G. Thomas, T.J. Causon, and I.K. Webb, et al. 2017. "Integrating Ion Mobility Spectrometry into Mass Spectrometry-based Exposome Measurements: What Can It Add and How Far Can It Go?." Bioanalysis 9, no. 1:81-98. PNNL-SA-121158. doi:10.4155/bio-2016-0244


  • Kabilan S., S.R. Suffield, K.P. Recknagle, R.E. Jacob, D.R. Einstein, A.P. Kuprat, and J.P. Carson, et al. 2016. "Computational Fluid Dynamics Modeling of Bacillus anthracis Spore Deposition in Rabbit and Human Respiratory Airways." Journal of Aerosol Science 99. PNNL-SA-108616. doi:10.1016/j.jaerosci.2016.01.011
  • Teeguarden J.G., N.C. Twaddle, M.I. Churchwell, and D.R. Doerge. 2016. "Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women." Food and Chemical Toxicology 92. PNNL-ACT-SA-10170. doi:10.1016/j.fct.2016.03.023
  • Teeguarden J.G., Y. Tan, S. Edwards, J.A. Leonard, K. Anderson, R.A. Corley, and M.L. Kile, et al. 2016. "Expanding on Successful Concepts, Models, and Organization." Environmental Science & Technology 50, no. 17:8921-8922. PNNL-SA-119240. doi:10.1021/acs.est.6b03027
  • Teeguarden J.G., Y. Tan, Y. Tan, S. Edwards, J.A. Leonard, K.A. Anderson, and R.A. Corley, et al. 2016. "Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework." Environmental Science & Technology 50, no. 9:4579-4586. PNNL-SA-114098. doi:10.1021/acs.est.5b05311
  • Zhang X., M.V. Romm, X. Zheng, E.M. Zink, Y. Kim, K.E. Burnum-Johnson, and D.J. Orton, et al. 2016. "SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in bio?uids." Clinical Mass Spectrometry 2. PNNL-SA-117436. doi:10.1016/j.clinms.2016.11.002


  • Teeguarden J.G., N.C. Twaddle, M.I. Churchwell, X. Yang, J. Fisher, L.M. Seryak, and D.R. Doerge. 2015. "24-Hour Human Urine and Serum Profiles of Bisphenol A: Evidence against Sublingual Absorption Following Ingestion in Soup." Toxicology and Applied Pharmacology 288, no. 2:131-142. PNNL-ACT-SA-10045. doi:10.1016/j.taap.2015.01.009
  • Teeguarden J.G., N.C. Twaddle, M.I. Churchwell, X. Yang, J.W. Fisher, L.M. Seryak, and D.R. Doerge. 2015. "24-Hour Human Urine and Serum Profiles of Bisphenol A Following Ingestion in Soup: Individual Pharmacokinetic Data and Demographics." Data in Brief 4. PNNL-ACT-SA-10050. doi:10.1016/j.dib.2015.03.002
  • Yang X., D.R. Doerge, J.G. Teeguarden, and J.W. Fisher. 2015. "Development of a physiologically based pharmacokinetic model for assessment of human exposure to bisphenol A." Toxicology and Applied Pharmacology 289, no. 3:442-456. PNNL-ACT-SA-10135. doi:10.1016/j.taap.2015.10.016


  • Asgharian B., O. Price, M. Oldham, L. Chen, E.L. Saunders, T. Gordon, and V.B. Mikheev, et al. 2014. "Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract." Inhalation Toxicology 26, no. 14:829-842. PNNL-SA-109668. doi:10.3109/08958378.2014.935535
  • Cohen J., J.G. Teeguarden, and P. Demokritou. 2014. "An integrated approach for the in vitro dosimetry of engineered nanomaterials." Particle and Fibre Toxicology 11. PNNL-SA-106412. doi:10.1186/1743-8977-11-20
  • LaKind J.S., J.R. Sobus, M. Goodman, D.B. Barr, P. Furst, R.J. Albertini, and T.E. Arbuckle, et al. 2014. "A Proposal for Assessing Study Quality: Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals (BEES-C) Instrument." Environment International 73. PNWD-SA-10307. doi:10.1016/j.envint.2014.07.011
  • Larson J.K., M.J. Carvan, J.G. Teeguarden, G. Watanabe, K. Taya, E. Krystofiak, and R.J. Hutz. 2014. "Low-dose gold nanoparticles exert subtle endocrine-modulating effects on the ovarian steroidogenic pathway ex vivo independent of oxidative stress." Nanotoxicology 8, no. 8:856-66. PNNL-SA-101177. doi:10.3109/17435390.2013.837208
  • Teeguarden J.G., V.B. Mikheev, K.R. Minard, W.C. Forsythe, W. Wang, G. Sharma, and N.J. Karin, et al. 2014. "Comparative Iron Oxide Nanoparticle Cellular Dosimetry and Response in Mice by the Inhalation and Liquid Cell Culture Exposure Routes." Particle and Fibre Toxicology 11. PNNL-SA-101188. doi:10.1186/s12989-014-0046-4


  • DeWoskin R.D., L.M. Sweeney, J.G. Teeguarden, R. Sams, and J. Vandenberg. 2013. "Comparison of PBTK Model and Biomarker Based Estimates of the Internal Dosimetry of Acrylamide." Food and Chemical Toxicology 58. PNWD-SA-9921. doi:10.1016/j.fct.2013.05.008
  • Kodali V.K., M.H. Littke, S.C. Tilton, J.G. Teeguarden, L. Shi, C.W. Frevert, and W. Wang, et al. 2013. "Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles." ACS Nano 7, no. 8:6997-7010. PNNL-SA-95359. doi:10.1021/nn402145t
  • Minard K.R., M.H. Littke, W. Wang, Y. Xiong, J.G. Teeguarden, and B.D. Thrall. 2013. "Magnetic Particle Detection (MPD) for In-Vitro Dosimetry." Biosensors and Bioelectronics 43. PNNL-SA-90647. doi:10.1016/j.bios.2012.12.011
  • Shankaran H., F. Adeshina, and J.G. Teeguarden. 2013. "Physiologically-Based Pharmacokinetic Model for Fentanyl in Support of the Development of Provisional Advisory Levels." Toxicology and Applied Pharmacology 273, no. 13:002464-476. PNWD-SA-10008. doi:10.1016/j.taap.2013.05.024
  • Sharma G., V.K. Kodali, M.J. Gaffrey, W. Wang, K.R. Minard, N.J. Karin, and J.G. Teeguarden, et al. 2013. "Iron Oxide Nanoparticle Agglomeration Influences Dose-Rates and Modulates Oxidative Stress Mediated Dose-Response Profiles In Vitro." Nanotoxicology 8, no. 6:663-675. PNNL-SA-93447. doi:10.3109/17435390.2013.822115
  • Teeguarden J.G., and S. Hanson-Drury. 2013. "A Systematic Review of Bisphenol A “Low Dose” Studies in the Context of Human Exposure: A Case for Establishing Standards for Reporting “Low- Dose” Effects of Chemicals." Food and Chemical Toxicology 62. PNWD-SA-10180. doi:10.1016/j.fct.2013.07.007
  • Teeguarden J.G., C. Housand, J.N. Smith, P.M. Hinderliter, R. Gunawan, and C. Timchalk. 2013. "A Multi-Route Model of Nicotine-Cotinine Pharmacokinetics, Pharmacodynamics and Brain Nicotinic Acetylcholine Receptor Binding in Humans." Regulatory Toxicology and Pharmacology 65, no. 1:12-28. PNNL-SA-92151. doi:10.1016/J.YRTPH.2012.10.007
  • Teeguarden J.G., J. Fisher, and D.R. Doerge. 2013. "Exposure Conditions and Pharmacokinetic Principles: Interpreting Bisphenol A Absorption in the Canine Oral Cavity." Environmental Health Perspectives 121, no. 11-12:A323-A323. PNWD-SA-10183. doi:10.1289/ehp.1307424
  • Teeguarden J.G., S. Hanson-Drury, J.W. Fisher, and D.R. Doerge. 2013. "Are Typical Human Serum BPA Concentrations Measureable and Sufficient to be Estrogenic in the General Population?." Food and Chemical Toxicology 62. PNWD-SA-10192. doi:10.1016/j.fct.2013.08.001


  • Karakoti A.S., P. Munusamy, K.E. Hostetler, V.K. Kodali, S.N. Kuchibhatla, G. Orr, and J.G. Pounds, et al. 2012. "Preparation and Characterization Challenges to Understanding Environmental and Biological Impacts of Ceria Nanoparticles." Surface and Interface Analysis 44, no. 8:881-889. PNNL-SA-83765. doi:10.1002/sia.5006
  • Teeguarden J.G., A. Calafat, and D.R. Doerge. 2012. "Adhering to Fundamental Principles of Biomonitoring, BPA Pharmacokinetics, and Mass Balance is no "Flaw"." Toxicological Sciences 125, no. 1:321-325. PNWD-SA-9573. doi:10.1093/toxsci/kfr275
  • Thrall B.D., K.R. Minard, J.G. Teeguarden, and K.M. Waters. 2012. Multiscale Toxicology - Building the Next Generation Tools for Toxicology. PNNL-21916. Richland, WA: Pacific Northwest National Laboratory. Multiscale Toxicology - Building the Next Generation Tools for Toxicology
  • Xie Y., N.G. Williams, A. Tolic, W.B. Chrisler, J.G. Teeguarden, B.L. Maddux, and J.G. Pounds, et al. 2012. "Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface." Toxicological Sciences 125, no. 2:450-461. PNNL-SA-83610. doi:10.1093/toxsci/kfr251


  • Baer D.R., A.S. Karakoti, P. Munusamy, B.D. Thrall, J.G. Pounds, J.G. Teeguarden, and J.E. Amonette, et al. 2011. "Testing in EHS: What is the Current Status of Experimentation?." In 11th IEEE International Conference on Nanotechnology (IEEE-NANO 2011), August 15-18, 2011, Portland, Oregon, 18-19. Piscataway, New Jersey:IEEE. PNNL-SA-90027. doi:10.1109/NANO.2011.6144671
  • Paur H., F.R. Cassee, J.G. Teeguarden, H. Fissan, S. Diabate, M. Aufderheide, and W.G. Kreyling, et al. 2011. "In-vitro Cell Exposure Studies for the Assessment of Nanoparticle Toxicity in the Lung - A Dialogue between Aerosol Science and Biology." Journal of Aerosol Science 42, no. 10:668-692. PNNL-SA-75727. doi:10.1016/j.jaerosci.2011.06.005
  • Teeguarden J.G., A. Calafat, X. Ye, D.R. Doerge, M.I. Churchwell, R. Gunawan, and M.K. Graham. 2011. "Twenty-Four Hour Human Urine and Serum Profiles of Bisphenol A during High-Dietary Exposure." Toxicological Sciences 123, no. 1:48-57. PNWD-SA-9583. doi:10.1093/toxsci/kfr160
  • Teeguarden J.G., B.M. Webb-Robertson, K.M. Waters, A. Murray, E. Kisin, S.M. Varnum, and J.M. Jacobs, et al. 2011. "Comparative Proteomics and Pulmonary Toxicity of Instilled Single Walled Carbon Nanotubes, Crocidolite Asbestos and Ultrafine Carbon Black in Mice." Toxicological Sciences 120, no. 1:123-135. PNNL-SA-74369. doi:10.1093/toxsci/kfq363


  • Hinderliter P.M., K.R. Minard, G. Orr, W.B. Chrisler, B.D. Thrall, J.G. Pounds, and J.G. Teeguarden. 2010. "ISDD: A Computational Model of Particle Sedimentation, Diffusion and Target Cell Dosimetry for In Vitro Toxicity Studies." Particle and Fibre Toxicology 7, no. November:Article No. 36. PNNL-SA-74873. doi:10.1186/1743-8977-7-36


  • Crump K.S., and J.G. Teeguarden. 2009. "Benchmark calculations from summarized data: an example." Environmental and Ecological Statistics 16, no. 1:13-24. PNNL-SA-62810.
  • Waters K.M., L.M. Masiello, R.C. Zangar, B.J. Tarasevich, N.J. Karin, R.D. Quesenberry, and S. Bandyopadhyay, et al. 2009. "Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes." Toxicological Sciences 107, no. 2:553-569. PNNL-SA-62659.


  • Dorman D.C., M.F. Struve, M.F. Struve, B.A. Wong, E.A. Gross, C. Parkinson, and G.A. Willson, et al. 2008. "Derivation of an Inhalation Reference Concentration Based Upon Olfactory Neuronal Loss in Male Rats Following Subchronic Acetaldehyde Inhalation." Inhalation Toxicology 20, no. 3:245-256. PNWD-SA-8184. doi:10.1080/08958370701864250
  • Nong A., J.G. Teeguarden, H.J. Clewell, III, D.C. Dorman, and M.E. Andersen. 2008. "Pharmacokinetic Modeling of Manganese in the Rat IV: Assessing Factors that Contribute to Brian Accumulation During Inhalation Exposure." Journal of Toxicology and Environmental Health Part A 71, no. 7:413-426. PNNL-SA-60107. doi:10.1080/15287390701838697
  • Teeguarden J.G., A. Gupta, P. Escobar, and M. Jackson. 2008. "Toxicology steps up to nanotechnology safety." Research & Development 50, no. 1:28-29. PNWD-SA-7902.
  • Teeguarden J.G., M.S. Bogdanffy, T.R. Covington, C. Tan, C. Tan, and A.M. Jarabek. 2008. "A PBPK Model for Evaluating the Impact of Aldehyde Dehydrogenase Polymorphisms on Comparative Rat and Human Nasal Tissue Acetaldehyde Dosimetry." Inhalation Toxicology 20, no. 4:375-390. PNWD-SA-8034. doi:10.1080/08958370801903750


  • Dutta D., S.K. Sundaram, J.G. Teeguarden, B.J. Riley, L.S. Fifield, J.M. Jacobs, and R.S. Addleman, et al. 2007. "Adsorbed Proteins Influence the Biological Activity and Molecular Targeting of Nanomaterials." Toxicological Sciences 100, no. 1:303-315. PNNL-SA-55139. doi:10.1093/toxsci/kfm217
  • Orr G., D.J. Panther, J.L. Phillips, B.J. Tarasevich, A. Dohnalkova, D. Hu, and J.G. Teeguarden, et al. 2007. "Submicron and Nanoscale Inorganic Particles Exploit the Actin Machinery to be Propelled Along Microvillilike Structures into Alveolar Cells." ACS Nano 1, no. 5:463-475. PNNL-SA-53625. doi:10.1021/nn700149r
  • Teeguarden J.G., D.C. Dorman, A. Nong, T.R. Covington, H.J. Clewell, III, and M.E. Andersen. 2007. "Pharmacokinetic Modeling of Manganese II. Hepatic Processing after Ingestion and Inhalation." Journal of Toxicology and Environmental Health Part A 70, no. 18:1505-1514. PNWD-SA-7554. doi:10.1080/15287390701384619
  • Teeguarden J.G., D.C. Dorman, T.R. Covington, H.J. Clewell, III, and M.E. Andersen. 2007. "Pharmacokinetic Modeling of Manganese I. Dose-Dependencies of Uptake and Elimination." Journal of Toxicology and Environmental Health Part A 70, no. 18:1493-1504. PNWD-SA-7553. doi:10.1080/15287390701384601
  • Teeguarden J.G., J. Gearhart, H.J. Clewell, III, T.R. Covington, A. Nong, and M.E. Anderson. 2007. "Pharmacokinetic Modeling of Manganese III. Physiological Approaches Accounting for Background and Tracer Kinetics." Journal of Toxicology and Environmental Health Part A 70, no. 18:1515-1526. PNNL-SA-52194. doi:10.1080/15287390701384635
  • Teeguarden J.G., P.M. Hinderliter, G. Orr, B.D. Thrall, and J.G. Pounds. 2007. "Particokinetics In Vitro: Dosimetry Considerations for In Vitro Nanoparticle Toxicity Assessments." Toxicological Sciences 95, no. 2:300-312. PNNL-SA-55055. doi:10.1093/toxsci/kfl165


  • Teeguarden J.G., J.M. Waechter, H.J. Clewell, III, T.R. Covington, and H.A. Barton. 2005. "Evaluation of Oral and IntravenousRoute Pharmacokinetics, Plasma Protein Binding and Uterine Tissue Dose Metrics of Bisphenol A: A Physiologically Based Pharmacokinetic Approach." Toxicological Sciences 85, no. 2:823-838. PNWD-SA-6845. doi:10.1093/toxsci/kfil135
  • Teeguarden J.G., P.J. Deisinger, T.S. Poet, J.C. English, W.D. Faber, H.A. Barton, and R.A. Corley, et al. 2005. "Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid." Toxicological Sciences 85, no. 1:429-446. PNNL-SA-42701.