PNNL

Gina Many is a biomedical scientist at Pacific Northwest National Laboratory (PNNL). Her research focuses on utilization of multi-omics data to understand complex biological systems. Currently, her work at PNNL centers around the NIH Common Fund Project, Molecular Transducers of Physical Activity Consortium (MoTrPAC). In MoTrPAC, her understanding of complex biological systems and multi-omics technologies has been key to generating biological insight into the integrative molecular responses to exercise within and across tissues. She has particular interest in understanding how the immune systems regulates cellular microenvironments and tissue remodeling in response to perturbations, such as physical exercise and disease, through application of multi-omic technologies.

• Systems biology
• Integrative omics
• Exercise Physiology
• Immunological systems
• Perturbations of biological systems
• Muscle remodeling

• PhD in Microbiology and Immunology, George Washington University, 2015
• MA in Exercise Physiology, University of Maryland, 2010
• BA in Exercise Science, George Washington University, 2005

• American College of Sports Medicine

2025

• You Y., G.M. Many, and E.S. Nakayasu. 2025. "Protein carbamylation and proteomics: from artifacts to elucidation of biological functions." Frontiers in Analytical Science 4:Art. No. 1512573. PNNL-SA-205105. doi:10.3389/frans.2024.1512573

2024

• Diaz Ludovico I., S.M. Powell, G.M. Many, L.M. Bramer, S. Sarkar, K.G. Stratton, and T. Liu, et al. 2024. "A fast and sensitive size-exclusion chromatography method for plasma extracellular vesicle proteomic analysis." Proteomics 24, no. 16:2400025. PNNL-SA-194254. doi:10.1002/pmic.202400025
• Estevao Da Silva I.L., J. Kazman, L.M. Bramer, C.D. Nicora, M. Qiang Ren, N. Sambuughin, and N. Munoz Munoz, et al. 2024. "The human plasma lipidome response to exertional heat tolerance testing." Lipids in Health and Disease 23, no. 1:Art No. 380. PNNL-SA-199090. doi:10.1186/s12944-024-02322-7
• Many G.M., J.A. Sanford, T.J. Sagendorf, Z. Hou, P. Nigro, K. Whytock, and D. Amar, et al. 2024. "Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue." Nature Metabolism 6, no. 5:963 - 979. PNNL-SA-181714. doi:10.1038/s42255-023-00959-9
• Schenk S., T.J. Sagendorf, G.M. Many, A.K. Lira, L.O. de Sousa, D. Bae, and M. Cicha, et al. 2024. "Physiological adaptations to progressive endurance exercise training in adult and aged rats: insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)." FUNCTION 5, no. 4:Art. No. zqae014. PNNL-SA-194543. doi:10.1093/function/zqae014