PNNL

Research and Professional Experience: 

Professional Experience:

1990 Postdoctoral Scientist, Laboratoire des Lesions des Acides Nucléique, Centre d’Etudes Nucléaires de Grenoble, Grenoble, France.

1991 - 1993 Postdoctoral Scientist, Radiobiology, Cross Cancer Institute, Edmonton, Alberta, Canada.

1993 – 1995 Postdoctoral Scientist, Institute of Molecular Biology and Biochemistry, Simon Fraser University, British Columbia, Canada.

1995-1999 Postdoctoral Scientist, Pacific Northwest National Laboratory, Richland, Washington, USA.

1999  Research Associate, Department of Radiology, Duke University Medical Center, Durham, North Carolina, USA.

2000  Research Associate, Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, USA.

2001 – Present  Senior Research Scientist, Biological Sciences Division and Seattle Structural Genomics Center for Infectious Disease, Pacific Northwest National Laboratory, Richland, Washington, USA.

2017 – Present  Associate Professor, School of Molecular Biosciences, Washington State University, Pullman, Washington, USA.

Synopsis:

I have been a Senior Research Scientist at Pacific Northwest National Laboratory (PNNL) since 2000 and recently accepted a Joint Appointment as an Associate Professor in the School of Molecular Biosciences at Washington State University in 2017. I have 35+ years of experience as a physical biochemist with specializations in protein chemistry, structural biology, and NMR spectroscopy. Over my career I have published over 150 peer-reviewed papers and personally deposited more than 50 protein structures into the PDB. The past 15 years has been devoted heavily on an NIH-funded biomineralization project and an NIAID-funded structural genomics project (Seattle Structural Genomics Center for Infectious Diseases, SSGCID). As one of the four founding SSGCID PIs, my primary role has been to determine structures of proteins recalcitrant to forming well-diffracting crystals using solution-state NMR methods and publish (36 SSGCID-associated publications). The biomineralization project involves understanding how the intrinsically disordered protein amelogenin orchestrates the formation of the hardest tissue in the human body, tooth enamel. 

• Structural Biology
• NMR spectroscopy
• Protein chemistry
• Protein expression
• Infectious diseases
• Biomineralization

• Doctor of Philosophy in Chemistry, University of Manitoba
• Master of Science in Chemistry, McMaster University
• Bachelor of Science in Biochemistry, University of Manitoba

• Associate Professor, School of Molecular Biosciences, WSU
• Seattle Structural Genomics Center for Infectious Diseases
• The Protein Society
• International Association for Dental Research

• Outstanding Performance Award, PNNL (2008, 2010, 2015)
• International Workshop on Radiation Damage in DNA Travel Award, 1994
• BC and Yukon Heart and Stroke Research Fellowship, 1993-1995
• Alberta Cancer Board Research Fellowship, 1991-1992
• Travel Award, American Association of Cancer Research, 1991
• France-Canada Postdoctoral Fellowship, Government of France, 1990
• Travel Award, A.N. Campbell, 1989