Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

The first direct molecular-scale evidence of the temperature-driven transformation of the coordination environment of ytterbium at geologically relevant conditions.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

PNNL researchers continue to deliver high-quality, high-impact research on radioactive waste and nuclear materials management, earning “Papers of Note” and “Superior Paper” awards.

Dušan Veličković, a PNNL mass spectrometry imaging scientist received a $2.1 million grant to develop techniques to understand how changes in carbohydrate structure affect human health.

PNNL researchers showcased subsurface sampling and remediation expertise at the 2025 Federal Remediation Technologies Roundtable.

PNNL has created and licensed a system that sniffs out trace levels of fentanyl, other drugs and explosives through the air.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Jeff Burghardt is the chair of the technical program for the 59th US Rock Mechanics/Geomechanics Symposium of the American Rock Mechanics Association.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

PNNL is hosting a scientific conference focused directly on understanding and predicting the collection of an organism’s traits.

Circadian rhythms of blue-green microbes offer new window into predictive phenomics—how to predict and control the traits of an organism.

Over the next four years, PNNL and University of Arizona will develop open-source computational tools to better identify and characterize the viruses associated with the human microbiome.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

RemPlex and IAEA convene international leaders to tackle recruitment and retention in complex environmental cleanup efforts.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

Led by interns from multiple DOE programs, a newly expanded dataset allows researchers to use easy-to-obtain measurements to determine the elemental composition of a promising carbon storage mineral.