Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

PNNL is hosting a scientific conference focused directly on understanding and predicting the collection of an organism’s traits.

Circadian rhythms of blue-green microbes offer new window into predictive phenomics—how to predict and control the traits of an organism.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

Scott Baker, the Functional and Systems Biology Group leader at PNNL, has been named to the American Institute for Medical and Biological Engineering's Class of 2024 Fellows.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

Research organizations work toward compelling market-ready solutions for building operations.

PNNL-developed Water Balance Tool estimates consumption for major water end-uses. Understanding the breakout of water use identifies water efficiency opportunities and allows facility managers to spot potential system losses.

Buildings account for around 40 percent of our nation's energy use and consume 75 percent of our nation’s electricity each year. Energy use is also one of the biggest costs for facility owners.

PNNL’s longstanding grid and buildings capabilities are driving two projects that test transactive energy concepts on a grand scale and lay the groundwork for a more efficient U.S. energy system.