Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Dušan Veličković, a PNNL mass spectrometry imaging scientist received a $2.1 million grant to develop techniques to understand how changes in carbohydrate structure affect human health.

PNNL has created and licensed a system that sniffs out trace levels of fentanyl, other drugs and explosives through the air.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

PNNL is hosting a scientific conference focused directly on understanding and predicting the collection of an organism’s traits.

Circadian rhythms of blue-green microbes offer new window into predictive phenomics—how to predict and control the traits of an organism.

Three PNNL technologies have been declared winners of 2025 Federal Laboratory Consortium Awards, named for a program that recognizes federal laboratories and their industry partners for outstanding technology transfer achievements.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

A cross-institutional team of scientists developed PeakQC, a new software tool for automated quality control of mass spectrometry data.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away.