Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.
The Pacific Northwest Association of Toxicologists (PANWAT) presented its annual Toxicology Achievement Award to Katrina Waters at the Society of Toxicology Pacific Northwest Chapter Meeting, held in Lynnwood, Washington, on September 30th.
PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.
Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.
Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.
Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.
This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.
New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.
PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.
New research findings published in Science Advances (November 2022), help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.
