PNNL has created and licensed a system that sniffs out trace levels of fentanyl, other drugs and explosives through the air.

Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

PNNL’s year in review includes highlights ranging from advancing soil science to understanding Earth systems, expanding electricity transmission, detecting fentanyl, and applying artificial intelligence to aid scientific discovery.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

National laboratory expertise was on display at the 2024 Department of Homeland Security Research, Development, Test, and Evaluation Summit.

In the latest issue of the Domestic Preparedness Journal, Ashley Bradley and Kristin Omberg share how new research is shedding light on the scientific and technological challenges with detecting fentanyl.

PNNL’s patented Shear Assisted Processing and Extrusion (ShAPE™) technique is an advanced manufacturing technology that enables better-performing materials and components while offering opportunities to reduce costs and energy consumption.

Scott Whalen, a chief scientist in the Applied Materials and Manufacturing group at PNNL, has been named 2023 PNNL Inventor of the Year

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

The next-generation ShAPE machine has arrived at PNNL, where it will help prove the mettle of the ShAPE extrusion technique. ShAPE 2 is designed to allow researchers to produce larger, more complex extrusions.

PNNL is supporting the Department of Homeland Security Science and Technology Directorate's Chemical Security Analysis Center in improving capabilities to enhance detection and analysis of chemical threats.

A new report highlights the results of an assessment PNNL conducted of field-portable detection products used by first responders to detect illicit substances like fentanyl in the field.

The 50th anniversary of the Finnish Institute for Verification of the Chemical Weapons Convention was recently celebrated in Helsinki, Finland. PNNL's Jonathan Forman and Raul Aranzazu attended this international event.