Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

The U.S. Nuclear Regulatory Commission approved the construction permit for Kairos Power’s Hermes molten salt test reactor project in Tennessee.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

Bradley Crowell with the U.S. Nuclear Regulatory Commission sees advanced materials integrity, radiological measurement, and environmental capabilities on his first visit to PNNL.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

PNNL’s ARENA test bed analyzes how electrical cables degrade in extreme environments and how nondestructive examination inspection technologies can detect and locate damage.

PNNL researchers explore the feasibility of using low-flying drones to survey sites for low levels of radiation.

As the world races to discover solutions for reaching net zero carbon emissions, a PNNL analysis quantifies the economic value of the existing nuclear power fleet and its carbon-free energy contributions.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

PNNL gathered researchers from eight national laboratories plus the U.S. Department of Energy (DOE) to share ideas and build synergy at the Energy Equity and Environmental Justice Summit.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.

Eight PNNL research papers were recognized by the 2022 Waste Management Symposia as “Papers of Note” and “Superior.” One paper received a Best Oral Paper/Presentation Award.