Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

Researchers used a combination of sophisticated laboratory incubations and field measurements to determine the role of microbial production and consumption of methane in soils with different exposure to tidal inundation

Researchers devised a quantitative and predictive understanding of the cloud chemistry of biomass-burning organic gases helping increase the understanding of wildfires.

Reproducible workflows for binning and visualizing nuclear magnetic resonance spectra from environmental samples.

Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.

A streamlined informatics workflow that automatically processes complex data and provides the locations of double bonds in lipids.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Hi-C metagenomics-informed phage-host infection networks detected in soil pre- and post-drying.

Mandy Mahoney, director of the DOE Building Technologies Office, visited PNNL in late November. One key agenda item involved meeting with staff for a discussion of effective equity and justice integration in buildings-related research.

Soil is a massive reservoir of carbon, holding three times the amount of carbon than in the atmosphere. Soil is a massive reservoir of carbon, holding three times the amount of carbon than in the atmosphere.

Metabolism metrics provide information about biological activity and carbon cycling in rivers. Conditions in large rivers differ from smaller rivers and require adjustments to existing methods.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.