Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

COMPASS points to understanding nature’s transition zones—areas that can be dry land at times and under water at others.

Understanding the Earth as a complex, dynamic system includes investigating what happens on, above and below its surface.

For decades, the Department of Energy's Pacific Northwest National Laboratory has played a role in establishing and maintaining sustainable hydropower for the region.