Thrust Area 1 Projects
PhenoProfiling
Science Objectives:
- Functionally enrich microbial communities and generate multi-omics to correlate biochemical mechanisms to activity.
- Integrate PhenoProfiling with Thrust Areas 2 and 3 to develop models for phenotype prediction and interspecies interactions.
- Evaluate enriched consortia for biochemical and molecular shifts as evidence of phenotypic changes related to soil carbon sequestration.
Profiling the Structural Proteome to Define Phenotype
Science Objective:
- Apply structural proteomics technologies to map the molecular interactome.
Multi-PTM Profiling for Molecular Phenotyping
Tong Zhang
Science Objective:
- Develop an integrated and automated multi-post-translational modification (PTM) profiling capability with deep proteome coverage.
Nanobodies to Control Phenome Transient Forms
Amy Sims & Samantha Powell
Science Objective:
- Use stimuli-specific, synthetic nanobodies to target functional mediators without prior knowledge of the response networks or manipulating the biological system.
Research topics
Lab-Level Communications Priority Topics
Biology